Results 61 to 70 of about 6,828 (261)
The Higgs signatures at the CEPC CDR baseline
Chinese Physics C, 2019 7 pages, 12 figures, submitted to Chinese Physics ...
Zhao, Hang +4 more
openaire +2 more sources
Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers
Annals of Neurology, EarlyView.Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang +45 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer +4 more
wiley +1 more source
Engineering Murine Cross‐Reactivity Into an Affibody to Human Death Receptor 5
Biotechnology and Bioengineering, EarlyView.ABSTRACT Interspecies cross‐reactive protein therapeutics that target conserved epitopes across species are critical for translational research. The present study showcases the engineering of an affibody molecule, originally discovered for binding to human death receptor 5 (hDR5) with 94 nM affinity, to simultaneously acquire cross‐reactivity to murine
Tse‐Han Kuo +3 more
wiley +1 more source
Scientific ReportsThis study investigates the colossal permittivity (CP) and humidity resistance of (Sn1/2Nb1/2)0.025Ti0.975O2 ceramics. Increasing the sintering temperature enhanced both density and grain growth, with the fine–grained structure proving essential for ...
Yasumin Mingmuang +4 more
doaj +1 more source
The Evolution of Adenoviral Vectors through Genetic and Chemical Surface Modifications
Viruses, 2014 A long time has passed since the first clinical trial with adenoviral (Ad) vectors. Despite being very promising, Ad vectors soon revealed their limitations in human clinical trials.
Cristian Capasso +3 more
doaj +1 more source
CDR-PoEt Policy Brief: Partizipation in CDR Politikgestaltung
This policy brief discusses how participatory processes for CDR policies can be designed and conducted.
Eberenz, Samuel +3 more
openaire +2 more sources
Engineered B7‐H3 Binding in Modular Gp2 Miniproteins
Biotechnology and Bioengineering, EarlyView.ABSTRACT B7‐H3, an important immune checkpoint modulator of T‐cell function, is a tumor vasculature biomarker and is overexpressed in a variety of cancers. Its expression is associated with tumor growth, metastasis, and poor clinical prognosis, which makes B7‐H3 an appealing target for diagnostics and therapeutics.
Abbigael Harthorn +5 more
wiley +1 more source
Business Strategy and the Environment, EarlyView.ABSTRACT Firms are increasingly looking into carbon dioxide removal (CDR), a set of options to take past emissions of greenhouse gases out of the atmosphere. Often two basic categories of CDR are distinguished: nature‐based solutions, such as planting trees or restoring wetlands, and technology‐based solutions, such as various forms of carbon capture ...
Sabrina Mili +3 more
wiley +1 more source
Tuning enhanced dielectric properties of (Sc3+–Ta5+) substituted TiO2 via insulating surface layers
Scientific ReportsIn this study, we achieved significantly enhanced giant dielectric properties (EG-DPs) in Sc3+–Ta5+ co-doped rutile-TiO2 (STTO) ceramics with a low loss tangent (tanδ ≈ 0.05) and high dielectric permittivity (ε′ ≈ 2.4 × 104 at 1 kHz).
Wattana Tuichai +3 more
doaj +1 more source