Results 161 to 170 of about 32,727 (270)

The GUIDE-CDSS framework: a comprehensive framework to GUIDE and evaluate the implementation of Clinical Decision Support Systems in healthcare, based on an overview of reviews. [PDF]

J Am Med Inform Assoc
Janssen ERC, Knoop J, Farabolini G, Baldini N, Hoogeboom T, Ceravolo MG, Negrini S, Kiekens C, PREPARE Project Group .   +8 more
europepmc   +1 more source

SIRT1 Silences L1 Retrotransposons by Stabilizing Heterochromatin‐Modifying Complexes

Aging Cell, Volume 25, Issue 9, September 2026.
SIRT1 binds the LINE‐1 5′‐UTR and recruits the heterochromatin modifiers Lamin B1 and KAP1 to maintain H3K9me3 levels, thereby suppressing LINE‐1 retrotransposition. SIRT1 deficiency enhances LINE‐1 transcription, leading to upregulation of senescence‐associated secretory phenotype factors, activation of the cGAS‐STING pathway, and consequent cellular ...
Xiaona Wang, Tianbo Li, Huanyin Tang, Meng Xiao Liu, Qinghua Peng, Xiao Huang, Zhiyong Mao, Ying Jiang, Anke Geng   +8 more
wiley   +1 more source

Technology‐Driven Decision Support for Opioid Tapering: A Scoping Review

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Background General practitioners manage most opioid tapering. This process requires time‐consuming, individualised planning accounting for patient preferences, dose options and costs. Consequently, clinicians need tools to support tapering.
Laurits Valberg Hemmingsen, Lærke Karner Overgaard, Uffe Kock Wiil, Daniel Pilsgaard Henriksen   +3 more
wiley   +1 more source

A Hybrid Rule-Based and Machine Learning-Based Clinical Decision Support System to Support Prescription Review: Development and External Validation Study. [PDF]

J Med Internet Res
Jeong J, Heo KN, Kim AJ, Baek JH, Jo YH, Kim S, Jo M, Ah YM, Han JM, Choi SW, Song J, Min S, Lee JY.   +12 more
europepmc   +1 more source

Epidemiological and Phylogenetic Analysis of Reassorted H10Nx Avian Influenza Viruses in Guangdong Province, China

Influenza and Other Respiratory Viruses, Volume 20, Issue 9, September 2026.
ABSTRACT Aims H10 subtype avian influenza viruses circulate widely among wild and domestic birds worldwide. These viruses have crossed species barriers to infect mammals, including humans, with cases of H10N3, H10N5 and H10N8 reported. During active surveillance in Guangdong Province, China, between 2023 and 2025, we isolated 10 H10Nx influenza A ...
Jie Liu, Qiyue Zhang, Haiyang Xiang, Yuanguo Li, Jing Liu, Qiucheng Yao, Yuwei Gao, Ye Ge   +7 more
wiley   +1 more source

Improving Medication Safety in Chronic Kidney Disease Using Rule-Based and Artificial Intelligence-Based Clinical Decision Support Systems: A Systematic Review of Randomized Controlled Trials. [PDF]

F1000Res
Ismail A, Sauriasari R, Yanuar A, Sudiana D, Cokro F.   +4 more
europepmc   +1 more source

The 3D genome of Gigaspora margarita unveils stable chromatin and nucleolar organization and symbiont‐dependent genome dynamics

New Phytologist, Volume 251, Issue 5, Page 2799-2817, September 2026.
Summary Arbuscular mycorrhizal fungi (AMF) are widespread plant symbionts that enhance nutrient acquisition and influence ecosystem productivity. Previous chromosome‐level assemblies of the model species Rhizophagus irregularis revealed a two‐compartment genome architecture (active A and repressed B chromatin compartments), yet its conservation across ...
Ken Mugambi, Jordana Oliveira, Franco Magurno, Alessandra Salvioli di Fossalunga, Mara Novero, Luisa Lanfranco, Stefano Ghignone, Gökalp Yildirir, Yan Wang, Paola Bonfante, Nicolas Corradi   +10 more
wiley   +1 more source

Performance of a clinical decision-support tool on empirical antibiotic treatment in the emergency department: a retrospective study. [PDF]

JAC Antimicrob Resist
Søgaard SN, Ward L, Mogensen ML, Mogensen CB, Cartuliares M, Skjøt-Arkil H.   +5 more
europepmc   +1 more source

Nonnodulating Fagales retain the functional NODULE INCEPTION gene

New Phytologist, Volume 251, Issue 6, Page 3080-3087, September 2026.
NODULE INCEPTION orthologs are present in nonnodulating species in Fagales.
Momona Noda, Momoyo Ito, Kana Miyata, Takuya Suzaki   +3 more
wiley   +1 more source

Barriers for Adoption of Analytical CDSS in Healthcare

, 2019
Most analytical Clinical Decision Support Systems (CDSS) remain within a research and development (R&D) environment and lack implementations in clinical contexts. This study discusses these implementation challenges as IT adoption barriers and gives possible solutions for these barriers.
Wijnhoven, Fons, Klein Koerkamp, Rick
openaire   +1 more source