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ИСКУССТВЕННЫЙ ИНТЕЛЛЕКТ В СППКР ПО ДАННЫМ ЭЛЕКТРОННЫХ МЕДИЦИНСКИХ КАРТ ДЛЯ ФЕНОТИПИРОВАНИЯ И ДИФФЕРЕНЦИАЛЬНОЙ ДИАГНОСТИКИ БАР И БДР

open access: yesCifra: Медико-биологические науки
Введение. Дифференциальная диагностика биполярного аффективного расстройства (БАР; bipolar disorder, BD) и униполярной депрессии (БДР; major depressive disorder, MDD) является сложной задачей, особенно на ранних стадиях заболевания.
Гоглов И.О.
doaj   +1 more source

Neighborhood Optimization for Therapy Decision Support

open access: yesCurrent Directions in Biomedical Engineering, 2019
This work targets the development of a neighborhood-based Collaborative Filtering therapy recommender system for clinical decision support. The proposed algorithm estimates outcome of pharmaceutical therapy options in order to derive recommendations. Two
Gräßer Felix   +2 more
doaj   +1 more source

Physician Compliance With a Computerized Clinical Decision Support System for Anemia Management of Patients With End-stage Kidney Disease on Hemodialysis: Retrospective Electronic Health Record Observational Study

open access: yesJMIR Formative Research, 2023
BackgroundPrevious studies on clinical decision support systems (CDSSs) for the management of renal anemia in patients with end-stage kidney disease undergoing hemodialysis have previously focused solely on the effects of the CDSS.
Ju-Yeh Yang   +9 more
doaj   +1 more source

The BnTFL1‐BnJAM3‐BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus

open access: yesAdvanced Science, EarlyView.
BnaC03.TFL1 and BnaA01.JAM3 form a complex that facilitates the transport of soluble sugars from the seed coat to the embryo by directly activating the expression of BnSWEETs. Furthermore, BnaC03.TFL1 and BnaA01.JAM3 work cooperatively to promote soluble sugar and oil production while suppressing protein deposition.
Jianjun Wang   +8 more
wiley   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun   +19 more
wiley   +1 more source

Natural Variation of COLD and CATECHINS REGULATOR 1 Coordinately Fine‐Tunes Cold Tolerance and Tea Quality in Tea Plants

open access: yesAdvanced Science, EarlyView.
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang   +10 more
wiley   +1 more source

Artificial intelligence in ophthalmic electronic medical records, health records, and registries

open access: yesKerala Journal of Ophthalmology
The integration of electronic health records (EHRs) and electronic medical records (EMRs) is fundamentally transforming ophthalmology by generating vast amounts of clinical data.
John Davis Akkara
doaj   +1 more source

Facilitators and Barriers to Interacting With Clinical Decision Support in the ICU: A Mixed-Methods Approach

open access: yesCritical Care Explorations, 2023
OBJECTIVES:. Clinical decision support systems (CDSSs) are used in various aspects of healthcare to improve clinical decision-making, including in the ICU. However, there is growing evidence that CDSS are not used to their full potential, often resulting
Adrian Wong, PharmD, MPH, FCCM, FCCP   +8 more
doaj   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

open access: yesAdvanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

Discrepancy between perceptions and acceptance of clinical decision support Systems: implementation of artificial intelligence for vancomycin dosing

open access: yesBMC Medical Informatics and Decision Making, 2023
Background Artificial intelligence (AI) tools are more effective if accepted by clinicians. We developed an AI-based clinical decision support system (CDSS) to facilitate vancomycin dosing.
Xinyan Liu   +7 more
doaj   +1 more source

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