Environmental Toxicology, EarlyView.ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida +7 more
wiley +1 more source
Combination of fecal SDC2 methylation with serum CEA/CA72-4 in screening of colorectal cancer and precancerous lesions. [PDF]
Clinics (Sao Paulo)Li Z +7 more
europepmc +1 more source
VIEW, EarlyView.We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen +9 more
wiley +1 more source
Right-lobe hepatic mucinous cystic neoplasm with an adjacent large hemorrhagic-appearing cyst: Markedly elevated serum CEA and CA19-9 despite benign imaging/pathology. [PDF]
Radiol Case RepMiyanaga T +5 more
europepmc +1 more source
VIEW, EarlyView.Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley +1 more source
Editorial: From molecules to function: the world of mesencephalic trigeminal nucleus neurons in health and disease. [PDF]
Front Cell NeurosciBae YC, Toyoda H, Kang Y.
europepmc +1 more source
VIEW, EarlyView.(A) Overview of the study population and schematic illustration showing tumor‐derived apoptotic and metabolic biomarkers, Apo10 and TKTL1, being phagocytosed by circulating monocytes and subsequently detected in peripheral blood. (B) Illustration of the epitope detection in monocytes (EDIM) strategy, using a flow‐cytometric gating approach based on ...
Zhiying Mao +8 more
wiley +1 more source
Normalization of CEA, CA15-3, and CA27-29 Tumor Markers Following Single Lung Transplant in a Patient With a History of Early-Stage Breast Cancer and Idiopathic Pulmonary Fibrosis: A Case Report. [PDF]
Cancer Rep (Hoboken)Chamorro Y, Vogel CL, Sandoval-Leon AC.
europepmc +1 more source
Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19-9 for overall survival in colorectal cancer. [PDF]
Oncol LettShi B +8 more
europepmc +1 more source
Origin and application of the Lorentz factor in X‐ray diffraction
Acta Crystallographica Section A, EarlyView.This review treats the role of the Lorentz factor in quantitative analysis of X‐ray diffraction data. The origin of the Lorentz factor, its derivation and practical implementations for a variety of modern X‐ray diffraction methods are discussed.The Lorentz factor is a fundamental correction factor in quantitative analysis of X‐ray diffraction ...
Fabian Gasser +5 more
wiley +1 more source