Results 71 to 80 of about 89,671 (248)

A review of the combined effects of climate change and other local human stressors on the marine environment.

open access: yesScience of the Total Environment, 2020
Climate change (CC) is a key, global driver of change of marine ecosystems. At local and regional scales, other local human stressors (LS) can interact with CC and modify its effects on marine ecosystems.
E. Gissi   +14 more
semanticscholar   +1 more source

Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang   +5 more
wiley   +1 more source

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

open access: yesAdvanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier   +16 more
wiley   +1 more source

25 ANOS DE CADERNOS DO CEAS

open access: yes, 2016
O CEAS entrevista Crisóstomo de Souza, Joviniano Neto e Cláudio Perani, que participaram da Equipe de Redação desde o ...
Ceas, Caderno
core  

A Novel tRNA Half mt‐5’‐tiRNA‐Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation

open access: yesAdvanced Science, EarlyView.
A mitochondria‐derived tRNA half, mt‐5’‐tiRNA‐Tyr, is upregulated in colorectal cancer tissues and plasma and promotes tumor proliferation. It binds HARS2 and promotes CPT1A‐associated HARS2 K91 succinylation, disrupts HARS2–mt‐tRNA‐His association, impairs mitochondrial translation, enhances succinate‐linked metabolic reprogramming, and shows promise ...
Xinliang Gu   +10 more
wiley   +1 more source

Isosorbide‐Based Optically Clear Adhesives With Ultrahigh Transparency and Rapid Strain Recovery for Flexible Displays

open access: yesAdvanced Science, EarlyView.
Biomass‐derived isosorbide‐based PUDA crosslinker enables optically clear adhesives with ultrahigh transparency (99.8%), rapid strain recovery, and stable adhesion for flexible displays. ABSTRACT Flexible and foldable displays require optically clear adhesives (OCAs) that combine ultrahigh optical transparency with mechanical resilience under repeated ...
Yoonji Choi   +8 more
wiley   +1 more source

CEAS: SAUDOSO E SAUDÁVEL

open access: yes, 2016
No título deste depoimento informal coloquei “CEAS saudoso” porque tenho dele uma lembrança muito afetuosa; e saudável porque foi nele que cresci em minha “saúde” e, ainda hoje, me inspira muito. Andando por estas regiões amazônicas, encontro pessoas que
Perani, Cláudio
core  

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu   +10 more
wiley   +1 more source

The combined effects of the cooling rate and alloying element on the mechanical behavior of Mg-Mn-Zn alloying system

open access: yesJournal of Alloys and Metallurgical Systems
Magnesium (Mg) alloys have recently been the subject of many investigations, as they show great potential for use in a multitude of applications. Due to their biocompatibility and attractive mechanical properties, one of the areas showing the greatest ...
Murtatha M. Jamel   +3 more
doaj   +1 more source

First joint CEAS/AIAA aeroacoustics conference. Proceedings. Vol. 1

open access: yes, 1995
The volumes I and II of the proceedings of the First Joint CEAS/AIAA Aeroacoustic Conference held in June 12-15, 1995 in Munich, Germany contain (69+71=) 140 papers. The papers deal with the following scientific subjects: computational aeroacoustics; jet
American Inst. of Aeronautics and Astronautics (AIAA), Washington, DC (United States)   +2 more
core  

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