Results 1 to 10 of about 142 (103)
SARS-CoV-2 viremia precedes an IL6 response in severe COVID-19 patients: results of a longitudinal prospective cohort [PDF]
Front Med (Lausanne), 2022 BackgroundInterleukin 6 (IL6) levels and SARS-CoV-2 viremia have been correlated with COVID-19 severity. The association over time between them has not been assessed in a prospective cohort.Roy-Vallejo E, Cardeñoso L, Triguero-Martínez A, Llano MC, Zurita N, Ávalos E, Barrios A, Hernando J, Ortiz J, Rodríguez-García SC, Sañudo MC, Marcos C, Castillo EG, García-Rodrigo LF, González B, Méndez R, Iturrate I, Sanz-García A, Villa A, Azofra AS, Quicios B, Arribas D, Rodríguez JÁ, Patiño P, Trigueros M, Uriarte M, Martín-Ramírez A, Arévalo Román C, Galván-Román JM, García-Vicuña R, Ancochea J, Calleja CM, Fernández-Ruiz E, de la Cámara R, Fernández CS, Álvaro IG, Rodríguez Serrano DA. +36 moreeuropepmc +3 more sourcesOccurrence of SARS-CoV-2 viremia is associated with genetic variants of genes related to COVID-19 pathogenesis. [PDF]
Front Med (Lausanne), 2023 IntroductionSARS-CoV-2 viral load has been related to COVID-19 severity. The main aim of this study was to evaluate the relationship between SARS-CoV-2 viremia and SNPs in genes previously studied by our group as predictors of COVID-19 severity.Materials Roy-Vallejo E, Fernández De Córdoba-Oñate S, Delgado-Wicke P, Triguero-Martínez A, Montes N, Carracedo-Rodríguez R, Zurita-Cruz N, Marcos-Jiménez A, Lamana A, Galván-Román JM, Villapalos García G, Zubiaur P, Ciudad M, Rabes L, Sanz M, Rodríguez C, Villa A, Rodríguez JÁ, Marcos C, Hernando J, Díaz-Fernández P, Abad F, de Los Santos I, Rodríguez Serrano DA, García-Vicuña R, Suárez Fernández C, P Gomariz R, Muñoz-Calleja C, Fernández-Ruiz E, González-Álvaro I, Cardeñoso L, PREDINMUN-COVID Group, Barrios A, Sanz J, Casado P, Gutiérrez Á, Bautista A, Hernández P, Ruiz Giménez N, Moyano B, Gil P, Jesús Delgado M, Parra P, Sánchez B, Sáez C, Fernández Rico M, Arévalo Román C, Castañeda S, Llorente I, G Tomero E, García Castañeda N, Uriarte M, Fontán García-Rodrigo L, Domingo García D, Alarcón Cavero T, Auxiliadora Semiglia Chong M, Gutiérrez Cobos A, Sánchez-Madrid F, Martín Gayo E, Sánchez-Cerrillo I, Martínez-Fleta P, López-Sanz C, Gabrie L, Del Campo Guerola L, Tejedor R, Ancochea J, García Castillo E, Ávalos E, Sánchez-Azofra A, Alonso T, Cisneros C, Valenzuela C, Javier García Pérez F, María Girón R, Aspa J, Marcos C, Del Perpetuo Socorro Churruca M, Zamora E, Martínez A, Barrio Mayo M, Henares Espi R, Méndez R, Arribas D, Chicot Llano M, González B, Quicios B, Patiño P, Trigueros M, Dominguez Peña C, Jiménez Jiménez D, Villamayor P, Canabal A, de la Cámara R, Ortiz J, Iturrate I. +94 moreeuropepmc +2 more sourcesDetection of SARS-Cov-2 RNA in serum is associated with increased mortality risk in hospitalized COVID-19 patients [PDF]
Sci Rep, 2021 COVID-19 has overloaded national health services worldwide. Thus, early identification of patients at risk of poor outcomes is critical. Our objective was to analyse SARS-CoV-2 RNA detection in serum as a severity biomarker in COVID-19.Rodríguez-Serrano DA, Roy-Vallejo E, Zurita Cruz ND, Ramírez AM, Rodríguez-García SC, Arevalillo-Fernández N, Galván-Román JM, García-Rodrigo LF, Vega-Piris L, Llano MC, Méndez DA, de Marcos BG, Santos JH, Azofra AS, Pérez-Urria EÁ, Rodriguez-Cortes P, Esparcia L, Marcos-Jimenez A, Sánchez-Alonso S, Llorente I, Soriano J, Fernández CS, García-Vicuña R, Ancochea J, Sanz J, Muñoz-Calleja C, de la Cámara R, Berlanga AC, González-Álvaro I, Cardeñoso L. +29 moreeuropepmc +3 more sourcesClinical features, genotypes, and geographic distribution of 238 Latin American CGD patients. [PDF]
J Hum ImmunThis epidemiological study describes CGD in Latin America. It highlights high infection risks, limited treatment options, and poor survival rates, especially for males with XL-CGD.Santos de Oliveira T, Salgado RC, Gomes LN, Aranda CS, Severo Ferreira JF, Goudouris ES, Mariz FP, Alonso MLO, Rodrigues Valle SO, Leite LFB, Ain ACDM, Roxo-Junior P, Montanaro M, de Medeiros Guimarães FAT, Resende Franco SC, Chong-Neto HJ, Rosario Filho NA, Bichuetti-Silva DC, Dantas VM, Franco JM, Mendes Barreto Resende VG, Lima SS, Costa DL, Dorna MB, Pastorino AC, Morgenstern B, Vagnozzi Rullo VE, Braga Cartaxo CG, de Sá NR, Paes Barreto ICD, Chen Lobo NV, Anisio de Carvalho FA, de Souza MS, Silva Segundo GR, de Moraes Vasconcelos D, Fernandes JF, Tusani GS, de Mello Prando CC, Diniz Iwamura APZ, López-Larios A, Carmona Vargas AJ, Macías-Robles AP, Gonzalez Serrano ME, Espinosa-Padilla SE, Peñafiel Vicuña AK, Staines-Boone AT, Saucedo-Ramírez OJ, García Domínguez M, Canseco-Raymundo MR, Saracho-Weber F, Martínez OZ, García-Pavón-Osorio S, Cotaya RG, Espinosa-Rosales FJ, Ramírez-Rivera R, García-Cruz MLH, Zarate-Hernández C, Blancas-Galicia L, King A, Porras O, Regairaz L, Lampugnani A, de Cuellar CM, Aldave Becerra JC, Espinoza LEV, Montenegro C, Schelotto M, Patiño V, de Oliveira MC, Condino-Neto A. +69 moreeuropepmc +2 more sourcesBaseline characteristics of patients with SLE with and without lupus nephritis from the Latin American multiethnic GLADEL 2.0 cohort. [PDF]
Lupus Sci MedObjective To describe baseline characteristics of a multinational, multiethnic Latin American cohort of SLE patients with and without lupus nephritis (LN) from Latin American Group for the Study of Lupus (GLADEL) 2.0.Methods GLADEL 2.0 is an ...Pons-Estel GJ, Nieto RE, Quintana R, Serrano Morales R, Borba EF, Hernández L, Harvey GB, Roberts K, Fernández-Ávila DC, Scolnik M, Funes Soaje C, Otaduy C, Saurit V, Arturi V, Berbotto GA, González Lucero L, Kerzberg E, Gómez GN, Pisoni CN, Juárez V, Martínez Serventi J, Isnardi CA, Parente Costa Seguro L, Montadon ACOS, Monticielo OA, Mariz HA, Machado Ribeiro F, Dos Reis-Neto ET, Guerra I, Massardo L, Aroca Martínez G, Iglesias Gamarra A, Cañas CA, Quintana López G, Toro Gutiérrez CE, Moreno Álvarez MJ, Saavedra MA, Portela Hernández M, Pérez Cristóbal M, Fragoso Loyo H, Juárez-Vicuña Y, González-Bello YC, Abud-Mendoza C, Esquivel-Valerio JA, Langjahr P, Paats A, Mora Trujillo C, Ugarte-Gil MF, Calvo-Quiroz A, Muñoz Louis R, Rebella M, Danza Á, Sbarigia U, Zazzetti F, Orillion A, Gómez Puerta JA, Alarcon GS, Pons-Estel BA. +57 moreeuropepmc +2 more sourcesPSGL-1, ADAM8, and selectins as potential biomarkers in the diagnostic process of systemic lupus erythematosus and systemic sclerosis: an observational study. [PDF]
Front ImmunolBackgroundEarly diagnosis and treatment of Systemic lupus erythematosus (SLE) and Systemic sclerosis (SSc) present significant challenges for clinicians.San Antonio E, Silván J, Sevilla-Montero J, González-Sánchez E, Muñoz-Callejas A, Sánchez-Abad I, Ramos-Manzano A, Muñoz-Calleja C, González-Álvaro I, Tomero EG, García-Pérez J, García-Vicuña R, Vicente-Rabaneda EF, Castañeda S, Urzainqui A. +14 moreeuropepmc +2 more sourcesGenetic variants regulating the immune response improve the prediction of COVID-19 severity provided by clinical variables. [PDF]
Sci RepThe characteristics of the host are crucial in the final outcome of COVID-19. Herein, the influence of genetic and clinical variants in COVID-19 severity was investigated in a total of 1350 patients.Delgado-Wicke P, Fernández de Córdoba-Oñate S, Roy-Vallejo E, Alegría-Carrasco E, Rodríguez-Serrano DA, Lamana A, Montes N, Nicolao-Gómez A, Carracedo-Rodríguez R, Marcos-Jiménez A, Díaz-Fernández P, Galván-Román JM, Rabes-Rodríguez L, Sanz-Alba M, Álvarez-Rodríguez J, Villa-Martí A, Rodríguez-Franco C, Villapalos-García G, Zubiaur P, Abad-Santos F, de Los Santos I, Gomariz RP, García-Vicuña R, Muñoz-Calleja C, González-Álvaro I, Fernández-Ruiz E, PREDINMUN-COVID Group. +26 moreeuropepmc +2 more sources