Results 51 to 60 of about 9,063 (160)

Predictive analytical workflow for rapid structure elucidation and in silico toxicological qualification of an unidentified impurity in cefixime granules for oral suspension

Acta Pharmaceutica
During in-use stability testing of cefixime granules for oral suspension, an impurity with a relative retention time of 0.19 was consistently detected and increased during storage.
Mitrevska Ivana, Chachorovska Marina, Petrushevski Gjorgji   +2 more
doaj   +1 more source

Performance of PEN‐FAST and CEPH‐FAST for Cephalosporin Allergy Delabeling

Clinical and Translational Allergy, Volume 16, Issue 6, June 2026.
Evaluation of PEN‐FAST and CEPH‐FAST in 100 patients with cephalosporin allergy labels showed that PEN‐FAST reliably identified low‐risk patients suitable for direct drug challenge, while CEPH‐FAST demonstrated reduced diagnostic performance. ABSTRACT Background Unverified antibiotic allergy labels lead to suboptimal antimicrobial prescribing and ...
Deniz Göcebe, Hannah Nürnberg, Alexander Enk, Elham Khatamzas, Knut Schäkel   +4 more
wiley   +1 more source

Potentiation of Antibacterial Activity of Cefixime in Synergy with Cirsium arvense (L.) Scop. Against Resistant Bacterial Isolates

Medical Sciences Forum
Antibiotic resistance is a major health priority, with the concern over antibiotic resistance growing. The rise in antibiotic-resistant bacteria coupled with the limited new therapeutics puts pressure on community and hospital healthcare systems and ...
Zoobaria Zahid, Aref Kyyaly, Jamil Jubrail   +2 more
doaj   +1 more source

Oral third-generation cephalosporins in the treatment of community-acquired urinary tract infections [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2019
Cephalosporins are one of the most commonly used antimicrobials for the treatment of variety of bacterial infections. Prudent use of the third-generation cephalosporins is important for the control of spread of cephalosporin-resistant Gram-negative ...
Kozlov R.S., Palagin I.S., Golub A.V.
doaj   +1 more source

Utility of micellar liquid chromatography as an analytical tool for the estimation of three binary antibiotic mixtures. Application to biological fluids

Journal of Taibah University for Science, 2020
A reliable and sensitive micelle based liquid chromatography (MLC) was developed aiming to simultaneously estimate three binary antibiotic mixtures namely: cefixime (CFX) in combination with either linezolid (LNZ) (mixture Ι) or levofloxacin hemihydrate (
Fawzia Ibrahim, Galal Magdy, Mary E. K. Wahba   +2 more
doaj   +1 more source

Interplay Between Virulence Genes, Antimicrobial Resistance Profiles, and Biofilm Formation in Klebsiella pneumoniae Causing Urinary Tract Infections in North Lebanon

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
– Figure design (single panel) Central icon: K. pneumoniae cell Left panel – Virulence genes (icons): Adhesion: fimH, mrkD → strong biofilm Capsule/regulation: magA, rmpA Siderophores: entB, iucA → iron uptake Right panel – Outcomes: Biofilm strength (weak → strong gradient) Antibiotic resistance (ESBL, MDR) Bottom split: Hospital‐acquired → strong ...
Mazen Zaylaa, Rayan Farha, Jana Taleb, Amal Saad, Omar El Gharbawy, Ricardo Sarraf, Ibtihal Kassam, Chadi Hamdach, Nisrine Bissar   +8 more
wiley   +1 more source

Carbapenem‐Resistant Gram‐Negative Bacilli in Mauritania: A Major Public Health Threat

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Carbapenem‐resistant Gram‐negative bacilli remain uncommon (4.42%) in Mauritania but are dominated by Klebsiella pneumoniae and Escherichia coli. Preserved activity of colistin, tigecycline, and amikacin highlights a narrowing therapeutic window and the urgent need for sustained surveillance and antimicrobial stewardship.
Fatimetou Ahmed Sid'Ahmed, Aminetou Mohamed Abbe, Mohamed Lemine Salem   +2 more
wiley   +1 more source

Guidelines for Essential Trauma Care: Second Edition (2026)

World Journal of Surgery, Volume 50, Issue 6, Page 1409-1450, June 2026.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock, Timothy C. Hardcastle, Christine Gaarder, Amit Gupta, Adam Gyedu, Manjul Joshipura, Elmin Steyn, on behalf of the Essential Trauma Care revision author group, Valencia Adjei, Roger Alcock, Vanda Amado, Michael Boampong, Sanjeev Booi, Petra Brysiewicz, Corazon Cabanilla‐Manuntag, Cristiane de Alencar Domingues, Ghada Elhadari, Ranjith Nanda Ellawala, Sarnai Erdene, Ama Akoma Essuman, Jorge Esteban Foianini, Filippo Gatti, Armando Garcia Guererra, Greg Hynes, Adil Haider, Sandy Ingless, Balavenkata Jagannathan, Helen Jowett, Knut Magne Kolstadbråten, Sonja Krofak, Aireen Patricia Madrid, Tina Tomić Mahečić, Claude Martin, Daniel Ntogwrachu, Bisola Onajin‐Obembe, Nhobojit Roy, Andres Rubiano, Niisoja Mensah Torto, Ben Wachira, Meg Walmsley, Torben Wisborg, Elma Wong   +41 more
wiley   +1 more source

Exploring the Antimicrobial Efficacy of Mesenchymal Stem Cell Secretome Against Klebsiella pneumoniae in Urinary Tract Infections

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Antimicrobial resistance (AMR) has become a global health crisis, with Klebsiella pneumoniae (K. pneumoniae) emerging as a major driver of AMR and a leading cause of urinary tract infections (UTIs). Mesenchymal stem cell (MSC)‐derived secretomes have gained attention for their antimicrobial properties.
Leen Ali, Elie Salem Sokhn, Charbel Khalil, Fatima A. Saleh   +3 more
wiley   +1 more source

Effect of sub MIC for Imipenem, Amikacin and Cefixime on Growth and Swarming of Proteus mirabilis

Journal of Pure and Applied Microbiology, 2018
The purpose of the present study is to evaluate the effect sub minimum inhibitory concentration (MIC) of imipenem, amikacin and cefixime on growth and swarming of Proteus mirabilis.
Hayder Hamzah Ibrahim, Naeem Rahman aljeburi, Muna Sabbar Jebar, Mustafa Ali Gayeb, Saher Saleh Mahdi, Hadeer Ali Kudder, Marwa Majed Naseer   +6 more
doaj   +1 more source