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Horizontal Gene Transfer of Fluoroquinolone Resistance-Conferring Genes From Commensal Neisseria to Neisseria gonorrhoeae: A Global Phylogenetic Analysis of 20,047 Isolates

open access: yesFrontiers in Microbiology, 2022
Antimicrobial resistance in Neisseria gonorrhoeae is an important global health concern. The genetically related commensal Neisseria act as a reservoir of resistance genes, and horizontal gene transfer (HGT) has been shown to play an important role in ...
Sheeba S Basil   +2 more
exaly   +3 more sources

Resistance Mechanisms and Molecular Epidemiology of Neisseria gonorrhoeae with Low Susceptibility/Resistance to Azithromycin or Cephalosporins [PDF]

open access: yesInfection and Drug Resistance
Sucai Chen,1 Fangyuan Xia2 1Clinical Laboratory Department, Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, Wenzhou, Zhejiang, People’s Republic of China; 2Department of Pharmacy, Wenzhou Hospital of Integrated Traditional ...
Chen S, Xia F
doaj   +2 more sources

Evaluation of a Hydrogel-Based Diagnostic Approach for the Point-of-Care Based Detection of Neisseria gonorrhoeae

open access: yesAntibiotics, 2018
Eleven primer pairs were developed for the identification of Neisseria gonorrhoeae. The sensitivity and specificity of these primers were evaluated by Real Time (RT)-PCR melt curve analyses with DNA from 145 N. gonorrhoeae isolates and 40 other Neisseria
Sumudu R Perera   +2 more
exaly   +3 more sources

Lipooligosaccharides (LOS) of Neisseria gonorrhoeae and Neisseria meningitidis have components that are immunochemically similar to precursors of human blood group antigens. Carbohydrate sequence specificity of the mouse monoclonal antibodies that recognize crossreacting antigens on LOS and human erythrocytes. [PDF]

open access: yesJournal of Experimental Medicine, 1988
We have used mouse mAbs, 3F11 and 06B4, that are specific for highly conserved epitopes of Neisseria gonorrhoeae lipooligosaccharides (LOS) to identify immunochemically similar structures on human erythrocytes. mAb 3F11 agglutinated erythrocytes from all
Griffiss, J, Macher, B, Mandrell, R
exaly   +2 more sources

Research progress on new antibiotics in the treatment of Neisseria gonorrhoeae infection [PDF]

open access: yesXin yixue, 2022
Neisseria gonorrhoeae is the pathogen of gonorrhea. With the widespread use of antibiotics, drug resistance of Neisseria gonorrhoeae is a growing problem.
Zhong Jiaojiao, Su Xiaohong
doaj   +1 more source

Neisseria gonorrhoeae Infections [PDF]

open access: yesPathogens, 2020
Gonorrhea is a sexually transmitted disease with a high morbidity burden. Despite having guidelines for its treatment, the incidence of the disease follows an increasing trend worldwide. This is mainly due to the appearance of antibiotic-resistant strains, inefficient diagnostic methods and poor sexual education. Without an effective vaccine available,
Beatriz Suay-García   +1 more
openaire   +3 more sources

Choosing New Therapies for Gonorrhoea: We Need to Consider the Impact on the Pan-Neisseria Genome. A Viewpoint

open access: yesAntibiotics, 2021
The development of new gonorrhoea treatment guidelines typically considers the resistance-inducing effect of the treatment only on Neisseria gonorrhoeae. Antimicrobial resistance in N.
Chris Kenyon   +2 more
doaj   +1 more source

Neisseria mucosa Does Not Inhibit the Growth of Neisseria gonorrhoeae

open access: yesSci, 2022
Antibiotic-sparing treatments are required to prevent the further emergence of antimicrobial resistance in Neisseria gonorrhoeae. Commensal Neisseria species have previously been found to inhibit the growth of pathogenic Neisseria species. For example, a
Saïd Abdellati   +8 more
doaj   +1 more source

Antimicrobial Resistance Profiles of Human Commensal Neisseria Species

open access: yesAntibiotics, 2021
Pathogenic Neisseria gonorrhoeae causes the sexually transmitted infection gonorrhea. N. gonorrhoeae has evolved high levels of antimicrobial resistance (AR) leading to therapeutic failures even in dual-therapy treatment with azithromycin and ceftriaxone.
Maira Goytia   +3 more
doaj   +1 more source

Analysis of the resistance to 7 antimicrobial agents in 100 strains of Neisseria gonorrhoeae

open access: yesPifu-xingbing zhenliaoxue zazhi, 2020
Objective: To analyse antimicrobial resistance of Neisseria gonorrhoeae to 7 antimicrobial agents and the penicillinase-producing Neisseria gonorrhoeae (PPNG) and tetracycline resistant Neisseria gonorrhoeae (TRNG) in Guangzhou during 2019.
Xiao-dong LI   +6 more
doaj   +1 more source

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