Results 21 to 30 of about 28,868 (173)

Resistance of Neisseria Gonorrhoeae to Neutrophils [PDF]

Frontiers in Microbiology, 2011
Infection with the human-specific bacterial pathogen Neisseria gonorrhoeae triggers a potent, local inflammatory response driven by polymorphonuclear leukocytes (neutrophils or PMNs). PMNs are terminally differentiated phagocytic cells that are a vital component of the host innate immune response and are the first responders to bacterial and fungal ...
Johnson, M. Brittany, Criss, Alison K.
openaire   +3 more sources

Opa-interacting protein 5 modulates docetaxel-induced cell death via regulation of mitophagy in gastric cancer

Tumor Biology, 2017
Damage to mitochondria induces mitophagy, a cellular process that is gaining interest for its therapeutic relevance to a variety of human diseases. However, the mechanism underlying mitochondrial depolarization and clearance in mitophagy remains poorly ...
Tae Woo Kim, Seon-Jin Lee, Young-Jun Park, Sang Yoon Park, Byung Moo Oh, Yun Sun Park, Bo-Yeon Kim, Young-Ha Lee, Hee Jun Cho, Suk Ran Yoon, Yong-Kyung Choe, Hee Gu Lee   +11 more
doaj   +1 more source

Loop-Mediated Isothermal Amplification Assay for Identifying Neisseria gonorrhoeae Nonmosaic penA-Targeting Strains Potentially Eradicable by Cefixime

Microbiology Spectrum, 2022
Treatment regimens for gonorrhea have limited efficacy worldwide due to the rapid spread of antimicrobial resistance. Cefixime (CFM) is currently not recommended as a first-line treatment for gonorrhea due to the increasing number of resistant strains ...
Ken Shimuta, Hideyuki Takahashi, Yukihiro Akeda, Shu-ichi Nakayama, Makoto Ohnishi   +4 more
doaj   +1 more source

RESISTÊNCIA AOS ANTIBIÓTICOS EM NEISSERIA GONORRHOEAE – PASSADO, PRESENTE E FUTURO

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2013
Introdução: A resistência aos antibióticos em Neisseria gonorrhoeae tem-se revelado um importante problema de saúde pública mundial, estando a levantar grandes dificuldades em termos de opções terapêuticas em alguns países.
Ermelindo Tavares, Cândida Fernandes, Maria José Borrego, Ana Rodrigues, Jorge Cardoso   +4 more
doaj   +1 more source

Rifampicin Resistance Associated with rpoB Mutations in Neisseria gonorrhoeae Clinical Strains Isolated in Austria, 2016 to 2020

Microbiology Spectrum, 2022
Due to increasing rates of antimicrobial resistance (AMR) in Neisseria gonorrhoeae, alternative treatments should be considered. To assess rifampicin’s potential as a gonorrhea treatment, we used rpoB mutations to estimate rifampicin resistance in ...
Justine Schaeffer, Kathrin Lippert, Sonja Pleininger, Anna Stöger, Petra Hasenberger, Silke Stadlbauer, Florian Heger, Angelika Eigentler, Alexandra Geusau, Alexander Indra, Franz Allerberger, Werner Ruppitsch   +11 more
doaj   +1 more source

Integrated molecular, phenotypic and epidemiological surveillance of antimicrobial resistance in Neisseria gonorrhoeae in Germany

International Journal of Medical Microbiology
Numbers of infections with Neisseria gonorrhoeae are among the top three sexually transmitted infections (STI) worldwide. In addition, the emergence and spread of antimicrobial resistance (AMR) in Neisseria gonorrhoeae pose an important public-health ...
Kathleen Klaper, Hana Tlapák, Regina Selb, Klaus Jansen, Dagmar Heuer   +4 more
doaj   +1 more source

INFEKSI NEISSERIA GONORRHOEAE AKIBAT SEXUAL ABUSE PADA SEORANG ANAK PEREMPUAN

Majalah Kedokteran Andalas, 2008
AbstrakInfeksi Neisseria gonorrhoeae pada anak akibat sexual abuse sangat jarang dilaporkan.Dilaporkan satu kasus infeksi Neisseria gonorrhoeae pada seorang anak perempuan usia 6 tahun setelah mengalami sexual abuse satu minggu yang lalu.Diagnosis ...
Satya Wydya Yenny
doaj   +1 more source

Synthetic DNA Delivery of an Optimized and Engineered Monoclonal Antibody Provides Rapid and Prolonged Protection against Experimental Gonococcal Infection

mBio, 2021
Neisseria ...
Elizabeth M. Parzych, Sunita Gulati, Bo Zheng, Mamadou A. Bah, Sarah T. C. Elliott, Jacqueline D. Chu, Nancy Nowak, George W. Reed, Frank J. Beurskens, Janine Schuurman, Peter A. Rice, David B. Weiner, Sanjay Ram   +12 more
doaj   +1 more source

Canary in the Coal Mine: How Resistance Surveillance in Commensals Could Help Curb the Spread of AMR in Pathogenic Neisseria

mBio, 2022
Antimicrobial resistance (AMR) is widespread within Neisseria gonorrhoeae populations. Recent work has highlighted the importance of commensal Neisseria (cN) as a source of AMR for their pathogenic relatives through horizontal gene transfer (HGT) of AMR ...
Maira Goytia, Crista B. Wadsworth
doaj   +1 more source

Microbisporicin (NAI-107) protects Galleria mellonella from infection with Neisseria gonorrhoeae

Microbiology Spectrum, 2023
Due to the increasing incidence of antibiotic-resistant bacterial pathogens, the need for the development of alternative compounds is of utmost importance. Bacteriocins are considered a promising alternative to antibiotics.
Nele Hofkens, Zina Gestels, Said Abdellati, Irith De Baetselier, Philippe Gabant, Anandi Martin, Christopher Kenyon, Sheeba Santhini Manoharan-Basil   +7 more
doaj   +1 more source