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Pyrrolopyrimidine derivatives as dual COX-2/ACE2 inhibitors: design, synthesis, and anti-inflammatory evaluation. [PDF]
Front Mol BiosciAfifi H +8 more
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Design and synthesis of novel spirocyclic oxindole based hybrid scaffolds: <i>in silico</i> docking approach towards therapeutic target exploration. [PDF]
RSC AdvUpadhyay RK +6 more
europepmc +1 more source
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Anti-Cancer Drugs, 2012
Cox-2 inhibitors have been identified as promising candidates for cancer therapy. Several studies have recently proposed the use of celecoxib in long-term low-intensity chemotherapy protocols for recurrent tumors. However, drug-induced hypersensitivity reactions may force discontinuation of the medication and, thus, significantly complicate successful ...
Guido J, Burbach +2 more
openaire +2 more sources
Cox-2 inhibitors have been identified as promising candidates for cancer therapy. Several studies have recently proposed the use of celecoxib in long-term low-intensity chemotherapy protocols for recurrent tumors. However, drug-induced hypersensitivity reactions may force discontinuation of the medication and, thus, significantly complicate successful ...
Guido J, Burbach +2 more
openaire +2 more sources