Results 141 to 150 of about 11,485,087 (317)

Assessment of Stem Cell Viability through Visual Analysis Coupled with Teachable Machine

open access: yes
Cell viability is an indispensable aspect of cells in the field of drug discovery, cell biology, and biomedical research to assess the physiological conditions of cells such as healthiness, functionality, survivability, etc.
Ryu, Dongryeol   +7 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

3 300 V IGBT / FRD Chipset Design and Development for Traction Application

open access: yes机车电传动, 2013
According to the IGBT characteristics and requirements for traction application, the simulation technique was used on the termination structure design to improve the blocking voltage.
LIU Guo-you   +3 more
doaj  

DEVELOPMENT OF LOW-TEMPERATURE CELL FOR IR FOURIER-SPECTROSCOPY OF HYDROCARBON MATERIALS

open access: yesEurasian Physical Technical Journal
This work introduces a technology for Fourier-Transform InfraRed spectroscopy of hydrocarbon materials at low temperatures and atmospheric pressure. This device allows to study optical properties of various substances at temperature range of 77 – 300 K ...
A. Kenbay, D. Yerezhep, A. Aldiyarov
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

FXR Regulates Intestinal Cancer Stem Cell Proliferation

open access: yes, 2019
Increased levels of intestinal bile acids (BAs) are a risk factor for colorectal cancer (CRC). Here, we show that the convergence of dietary factors (high-fat diet) and dysregulated WNT signaling (APC mutation) alters BA profiles to drive malignant ...
황성순
core   +1 more source

Observations of cellular responses to diamagnetic forces acting on cell components

open access: yesScience and Technology of Advanced Materials, 2008
The magnetooptical measurements of the properties of living cells have a potentially large impact on cellular engineering and biotechnology because the noninvasive approach to applying magnetic fields on cells enables the detection of the dynamics of ...
Masakazu Iwasaka et al
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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