Results 181 to 190 of about 26,893,016 (421)
How matrix metalloproteinases regulate cell behavior.
Annual Review of Cell and Developmental Biology, 2001 The matrix metalloproteinases (MMPs) constitute a multigene family of over 25 secreted and cell surface enzymes that process or degrade numerous pericellular substrates.
M. Sternlicht, Z. Werb
semanticscholar +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Editorial: Cancer Cell Mechanobiology - A New Frontier for Cancer Invasion and Metastasis Research
Frontiers in Cell and Developmental Biology, 2021 Jianyu Rao +4 more
doaj +1 more source
Applied SciencesLinear spatial data are primarily used in Geographic Information Systems (GISs) to represent spatial data in the form of roads, rivers, railways, and utility lines. Linear spatial data are mostly composed of one-dimensional linear elements, incorporating
Kyu Soo Chong
doaj +1 more source
Unsupervised Segmentation of Overlapping Cervical Cell Cytoplasm [PDF]
arXiv, 2015 Overlapping of cervical cells and poor contrast of cell cytoplasm are the major issues in accurate detection and segmentation of cervical cells. An unsupervised cell segmentation approach is presented here. Cell clump segmentation was carried out using the extended depth of field (EDF) image created from the images of different focal planes. A modified
arxiv
Molecular Oncology, EarlyView.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source
Pitchfork Bifurcation In A Coupled Cell System [PDF]
arXivVarious biological phenomena, like cell differentiation and pattern formation in multicellular organisms, are explained using the bifurcation theory. Molecular network motifs like positive feedback and mutual repressor exhibit bifurcation and are responsible for the emergence of diverse cell types.
arxiv
A stochastic modeling framework for single cell migration: coupling contractility and focal adhesions [PDF]
arXiv, 2018 The interaction of the actin cytoskeleton with cell-substrate adhesions is necessary for cell migration. While the trajectories of motile cells have a stochastic character, investigations of cell motility mechanisms rarely elaborate on the origins of the observed randomness.
arxiv
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Cells in quantum affine sl_n [PDF]
arXiv, 2002 We study Lusztig's theory of cells for quantum affine $\mathfrak{sl}_n$. Using the geometric construction of the quantum group due to Lusztig and Ginzburg--Vasserot, we describe explicitly the two-sided cells, the number of left cells in a two--sided cell, and the asymptotic algebra, verifying conjectures of Lusztig.
arxiv