Results 11 to 20 of about 11,901,652 (317)

p57(Kip2) imposes the reserve stem cell state of gastric chief cells

, 2022
Adult stem cells constantly react to local changes to ensure tissue homeostasis. In the main body of the stomach, chief cells produce digestive enzymes; however, upon injury, they undergo rapid proliferation for prompt tissue regeneration.
Ju, Young Seok, Caldwell, Brianna, Wu, Szu-Hsien Sam, Choi, Eunyoung, Stange, Daniel E., Park, JinYoung, Bamford, Aileen-Diane, Kim, Somi, Kim, Jihoon, An, Yohan, Bon-kyoung Koo, Kim, Jong Kyoung, Rocha, Andreia Sofia Batista, Pilat-Carotta, Sandra, Josserand, Manon, Lee, Heetak, Han, Seungmin, Lee, Ji-Hyun, Philpott, Anna, Fink, Juergen, Szep-Bakonyi, Réka, Min, Jimin, Koo, Bon-Kyoung, Lee, Sieun, Simons, Benjamin D., Aileen-Diane Bamford, Heetak Lee, Sandra Pilat-Carotta, Réka Szep-Bakonyi, Somi Kim, Jimin Min, Szu-Hsien Sam Wu, Juergen Fink, JinYoung Park, Seungmin Han, Eunyoung Choi, Jong Kyoung Kim, Andreia Sofia Batista Rocha, Anna Philpott, Ji-Hyun Lee, Daniel E. Stange, Benjamin D. Simons, Sieun Lee, Brianna Caldwell, Yohan An, Jihoon Kim, Young Seok Ju, Manon Josserand   +47 more
core   +1 more source

Cells, Cells, and More Cells

Survey of Ophthalmology, 2007
A 64-year-old woman presented with bilateral optic nerve swelling, vitreous cells, and cerebrospinal fluid monocytic pleocytosis. A chest radiograph and computed tomography demonstrated a lesion in the left lung, which histologically was confirmed to be a small-cell lung carcinoma.
Departments of Ophthalmology and Medicine (Division of Neurology), Duke University Eye Center and Duke University Medical Center, Durham, North Carolina ( host institution ), Bhatti, M. Tariq, Gres, Katherine E., Petitto, Virginia B., Cross, Shelley Ann   +4 more
openaire   +3 more sources

Cdc42-mediated tubulogenesis controls cell specification. [PDF]

, 2009
SummaryUnderstanding how cells polarize and coordinate tubulogenesis during organ formation is a central question in biology. Tubulogenesis often coincides with cell-lineage specification during organ development. Hence, an elementary question is whether
Greiner, Thomas, Johansson, Jenny, Semb, Tor Henrik, Wolfhagen Sand, Fredrik,, Greiner, Thomas Uwe, Kesavan, Gokul,, Brakebusch, Cord, Greiner, Thomas,, Sand, Fredrik Wolfhagen, Johansson, Jenny,, Johansson, Jenny Kristina, Kobberup, Sune, Wolfhagen Sand, Fredrik, Kobberup, Sune,, Wu, Xunwei, Semb, Henrik, Semb, Henrik,, Lund University., Kesavan, Gokul   +18 more
core   +1 more source

The RANK/RANKL/OPG system and tumor bone metastasis: Potential mechanisms and therapeutic strategies

Frontiers in Endocrinology, 2022
With the markedly increased diagnosis and incidence of cancer in the population, tumor bone metastasis has become a frequent event in tumor patients. Healthy bone integrity is maintained by a delicate balance between bone formation and bone resorption ...
Yan Zhang, Jingqi Liang, Peilong Liu, Qiong Wang, Liang Liu, Hongmou Zhao   +5 more
doaj   +1 more source

Estimating Bacterial and Cellular Load in FCFM Imaging

Journal of Imaging, 2018
We address the task of estimating bacterial and cellular load in the human distal lung with fibered confocal fluorescence microscopy (FCFM). In pulmonary FCFM some cells can display autofluorescence, and they appear as disc like objects in the FCFM ...
Sohan Seth, Ahsan R. Akram, Kevin Dhaliwal, Christopher K. I. Williams   +3 more
doaj   +1 more source

Endogenous electric fields as guiding cue for cell migration

Frontiers in Physiology, 2015
This review is about the long-range action of endogenous electric fields (EF) within animal organisms. It covers two major topics: 1) the different functions of the EF during development of the organism as well as physiological and pathological roles of ...
Richard H. W. Funk
doaj   +1 more source

Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition [PDF]

, 2021
Checkpoint inhibitors (CPIs) augment adaptive immunity. Systematic pan-tumor analyses may reveal the relative importance of tumor-cell-intrinsic and microenvironmental features underpinning CPI sensitization.
Turati, Virginia, Rosenthal, R, Saini, SK, Rosenthal, Rachel, Herrero, Javier, Rowan, A, Turajlic, Samra, Litchfield, K, Guerra-Assunção, José Afonso, Turajlic, S, Hellmann, Matthew D., Swanton, C, Saini, Sunil Kumar, Larkin, James, McGranahan, Nicholas, Reading, JL, Puttick, C, Reading, James L., Swanton, Charles, Thakkar, K, Al Bakir, M, Conde, L, Lim, Emilia, Watkins, TBK, Biswas, D, Enver, Tariq, Puttick, Clare, Turati, V, Litchfield, Kevin, Watkins, Thomas B.K., Hellmann, MD, Rowan, Andrew, Lim, E, Biswas, Dhruva, Van Loo, P, Quezada, SA, Guerra-Assunção, JA, Quezada, Sergio A., Bentham, Robert, Herrero, J, Enver, T, Furness, Andrew J.S., Hadrup, Sine R., Conde, Lucia, Hadrup, SR, Abbosh, C, Lee, Se Hoon, Furness, AJS, Lee, S-H, Al Bakir, Maise, Abbosh, Chris, McGranahan, N, Bentham, R, Larkin, J, Van Loo, Peter, Thakkar, Krupa, James L. Reading, Sunil Kumar Saini, Samra Turajlic, Maise Al Bakir, Nicholas McGranahan, Rachel Rosenthal, Kevin Litchfield, Matthew D. Hellmann, José Afonso Guerra-Assunção, Charles Swanton, Dhruva Biswas, Tariq Enver, Andrew Rowan, Sergio A. Quezada, Lucia Conde, Andrew J.S. Furness, Krupa Thakkar, Virginia Turati, Se-Hoon Lee, James Larkin, Javier Herrero, Robert Bentham, Peter Van Loo, Clare Puttick, Emilia Lim, Chris Abbosh, Sine R. Hadrup, Thomas B.K. Watkins   +83 more
core   +1 more source

Lipid Specific Membrane Interaction of Aptamers and Cytotoxicity

Membranes, 2021
We aim to discover diagnostic tools to detect phosphatidylserine (PS) externalization on apoptotic cell surface using PS binding aptamers, AAAGAC and TAAAGA, and hence to understand chemotherapy drug efficacy when inducing apoptosis into cancer cells ...
Md. Ashrafuzzaman, Hanouf A. M. AlMansour, Maha A. S. AlOtaibi, Zahid Khan, Gouse M. Shaik   +4 more
doaj   +1 more source

Cell Competition and its role in the regulation of cell fitness from development to cancer [PDF]

, 2016
Cell competition is a cell fitness-sensing mechanism conserved from insects to mammals that eliminates those cells that, although viable, are less fit than their neighbors. An important implication of cell competition is that cellular fitness is not only
di gregorio, A, Rodriguez, T, Bowling, S
core   +1 more source

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.

, 2022
Clear cell renal cell carcinoma (ccRCC) is characterized by near-universal loss of the short arm of chromosome 3, deleting several tumor suppressor genes. We analyzed whole genomes from 95 biopsies across 33 patients with clear cell renal cell carcinoma.
Raine, K, Yates, LR, Teague, J, Lopez, JI, Gore, M, Rowan, A, Mitchell, TJ, Lynch, AG, Au, L, Stewart, A, Litchfield, K, Turajlic, S, Tarpey, P, Chandra, A, Csabai, I, Swanton, C, Fotiadis, N, Lynch, J, Soultati, A, Challacombe, B, Xu, H, Hazell, S, Stamp, G, Elaidi, R, Horswell, S, Campbell, PJ, Chowdhury, S, Butler, AP, Rudman, S, Wedge, DC, Futreal, PA, Nicol, D, Farmery, JHR, O'Brien, T, Maura, F, McGranahan, N, TRACERx Renal Consortium,, Spain, L, Stewart, GD, Szallasi, Z, Martincorena, I, Stares, M, Fernando, A, Larkin, J, Oudard, S, Pickering, L, Chambers, T, Angelopoulos, N   +47 more
core   +1 more source