In vitro tubulogenesis of endothelial cells by relaxation of the coupling extracellular matrix-cytoskeleton [PDF]
Christophe Deroanne
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The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Modeling, Evaluation, and In Vivo Estimation of Muscle Cell Diameter With the Random Permeable Barrier Model: Correlation With Subject Characteristics and Isometric Torque. [PDF]
Froeling M +4 more
europepmc +1 more source
Measuring the stiffness of bacterial cells from growth rates in hydrogels of tunable elasticity [PDF]
Hannah H. Tuson +9 more
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PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Sex Matters: Hormonal and Chromosomal Determinants of Autoimmunity and Anti-Cancer Immunity Across the Lifespan. [PDF]
Bustillos CG +4 more
europepmc +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The X Factor in Immunity: Sex Differences Shaped by the X Chromosome. [PDF]
Radovanovic KB, Wynalda M, Anguera MC.
europepmc +1 more source
Filamin A (FLNA) is required for cell–cell contact in vascular development and cardiac morphogenesis
Yuanyi Feng +7 more
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