Results 211 to 220 of about 19,745,596 (363)

Design Of A Nonvolatile 8T1R SRAM Cell For Instant-On Operation

, 2016
J. Mounica, G. Ganesh
openalex   +2 more sources

Finding active LCH cells in the blood [PDF]

, 2017
Oussama Abla
openalex   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

RIPK1 as a potential target to augment DC efficacy in tumor immunotherapy. [PDF]

Cancer Immunol Immunother
Mao L, Ou Y, Zhang Y, Wang M, Dong G, Khanniche A, Wang H, Wu Z, Zhang H, Hu L, Kong X.   +10 more
europepmc   +1 more source

Correction to: Reassessing the clinical spectrum associated with Hereditary Leiomyomatosis and Renal Cell Carcinoma syndrome in French FH mutation carriers [PDF]

, 2018
M. Muller, Marine Guillaud‐Bataille, S. Richard, Patrick R. Benusiglio   +3 more
openalex   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Accessible and cost-effective methods for patterning cell monolayers on compliant substrates. [PDF]

PLoS One
McCord M, Khankhel AH, Kafkis K, Radtke G, Candan S, Kumar HA, Derksen P, Tam M, Zhou K, Merk MW, Franck C, Streichan SJ, Notbohm J.   +12 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Novel Cell Seeding System into a Porous Scaffold Using a Modified Low-Pressure Method to Enhance Cell Seeding Efficiency and Bone Formation

, 2007
Ichiro Torigoe, Shinichi Sotome, Akio Tsuchiya, Toshitaka Yoshii, M Takahashi, Shigenori Kawabata, Kenichi Shinomiya   +6 more
openalex   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source