Results 301 to 310 of about 19,745,596 (363)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Optimized protocol for dissociation of mouse intestinal epithelium to viable single-cells. [PDF]

STAR Protoc
Zhao N, Geng P, Ge Y.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Co-occurrence of angioimmunoblastic T-cell lymphoma and aggressive-refractory plasma-cell neoplasm: Two new cases and literature review. [PDF]

Clin Hematol Int
Cox MC, Seimonte C, Giacobbi E, Pasqualone G, Pupo L, Zizzari A, Franceschini L, Venditti A, Postorino M.   +8 more
europepmc   +1 more source

Association of CCL21⁺ CAFs with B-cell recruitment and TLS maturation in penile squamous cell carcinoma. [PDF]

Cancer Immunol Immunother
Li X, Chen D, Guo Y, Huang G, Cai Z, Xue T, Chen Z, Han H, Li Z.   +8 more
europepmc   +1 more source

Statement of Retraction: Deciphering cell-cell interactions and communication in the tumor microenvironment and unraveling intratumoral genetic heterogeneity via single-cell genomic sequencing. [PDF]

Bioengineered
europepmc   +1 more source

Biodegradable targeted polymeric mRNA nanoparticles enable in vivo CD19 CAR T cell generation and lead to B cell depletion. [PDF]

Sci Adv
Jain M, Est-Witte SE, Shannon SR, Neshat SY, Yu X, Dunham S, Tian T, Cheng L, Harris J, Konig MF, Tzeng SY, Schneck JP, Green JJ.   +12 more
europepmc   +1 more source