Sarcoidosis and COVID-19: At the Cross-Road between Immunopathology and Clinical Manifestation
Biomedicines, 2022 Coronavirus disease 2019 (COVID-19) has been associated with dysregulation of the immune system featuring inappropriate immune responses, exacerbation of inflammatory responses, and multiple organ dysfunction syndrome in patients with severe disease ...
Claudio Tana +11 more
doaj +1 more source
Physical Confinement and Cell Proximity Increase Cell Migration Rates and Invasiveness: A Mathematical Model of Cancer Cell Invasion through Flexible Channels [PDF]
, 2022 Cancer cell migration between different body parts is the driving force behind cancer metastasis, which is the main cause of mortality of patients. Migration of cancer cells often proceeds by penetration through narrow cavities in locally stiff, yet flexible tissues. In our previous work, we developed a model for cell geometry evolution during invasion,
arxiv +1 more source
Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma.
New England Journal of Medicine, 2015 BACKGROUND Nivolumab, a programmed death 1 (PD-1) checkpoint inhibitor, was associated with encouraging overall survival in uncontrolled studies involving previously treated patients with advanced renal-cell carcinoma.
R. Motzer +26 more
semanticscholar +1 more source
Blood Cell Classification Using the Hough Transform and Convolutional Neural Networks [PDF]
, 2018 https://doi.org/10.1007/978-3-319-77712-2_62The detection of red blood cells in blood samples can be crucial for the disease detection in its early stages.
Luque-Baena, Rafael Marcos +4 more
core +1 more source
Clinical presentation, management and follow-up of 83 patients with Leydig cell tumors of the testis: a prospective case-cohort study [PDF]
, 2019 LCTs are more frequent than generally believed, are associated with male infertility, cryptorchidism and gynecomastia, and should be treated conservatively (in compliant patients) with active surveillance, which appears to be a safe alternative to ...
Cantisani, Vito +12 more
core +1 more source
Cell-based therapies for stroke : promising solution or dead end? [PDF]
, 2020 The introduction of recanalization procedures has revolutionized acute stroke management, although the narrow time window, strict eligibility criteria and logistical limitations still exclude the majority of patients from treatment. In addition, residual
Abe, Koji +6 more
core +1 more source
Pharmaceuticals, 2023 This research presents a novel synthetic photosensitizer for the photodynamic therapy (PDT) of malignant tumors: meso-tetra(3-pyridyl) bacteriochlorin, which absorbs at 747 nm (in the long-wavelength region of the spectrum) and is stable when stored in ...
Ekaterina Plotnikova +6 more
doaj +1 more source
Surface activity of cancer cells: the fusion of two cell aggregates [PDF]
arXiv, 2021 Although a good comprehension of how cancer cells collectively migrate by following molecular rules which influence the state of cell-cell adhesion contacts has been generated, the impact of collective migration on cellular rearrangement from subcellular to supracellular level remains less understood.
arxiv
Cell-to-cell variation sets a tissue-rheology-dependent bound on collective gradient sensing [PDF]
PNAS (2017), 2017 When a single cell senses a chemical gradient and chemotaxes, stochastic receptor-ligand binding can be a fundamental limit to the cell's accuracy. For clusters of cells responding to gradients, however, there is a critical difference: even genetically identical cells have differing responses to chemical signals.
arxiv +1 more source
Cell-in-cell: A virgin land of cell biology [PDF]
OncoImmunology, 2013 Cell-in-cell affects multiple functions of both internalized and internalizing cells. Immune effector cells and their targets can also interact in this fashion. We have recently investigated the outcome of cell-in-cell, the molecular mechanisms underpinning this phenomenon, and its relevance in both physiological and pathological conditions.
Ying Wang, Xiaoning Wang
openaire +3 more sources