Results 101 to 110 of about 11,890,652 (305)

Short-term ex-vivo exposure to hydrogen sulfide enhances murine hematopoietic stem and progenitor cell migration, homing, and proliferation

open access: yesCell Adhesion & Migration, 2020
For successful transplantation of Hematopoietic Stem cells (HSCs), it is quite necessary that efficient homing, engraftment and retention of HSC self-renewal capacity takes place, which is often restricted due to inadequate number of adult HSCs. Here, we
Anoushka Khanna   +3 more
doaj   +1 more source

E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells

open access: yesJournal of Cell Biology, 1991
The ability of carcinomas to invade and to metastasize largely depends on the degree of epithelial differentiation within the tumors, i.e., poorly differentiated being more invasive than well-differentiated carcinomas.
U. Frixen   +5 more
semanticscholar   +1 more source

Focal Adhesion-Independent Cell Migration.

open access: yesAnnual Review of Cell and Developmental Biology, 2016
Cell migration is central to a multitude of physiological processes, including embryonic development, immune surveillance, and wound healing, and deregulated migration is key to cancer dissemination.
E. Paluch, Irene M. Aspalter, M. Sixt
semanticscholar   +1 more source

The Interaction of Src Kinase with β3 Integrin Tails: A Potential Therapeutic Target in Thrombosis and Cancer

open access: yesThe Scientific World Journal, 2010
Activation of Src family kinases is an important event downstream of integrin adhesion signaling in many cell types. A particularly intriguing connection between an integrin and a Src family kinase was first discovered in platelets, where the selective ...
Stephan Huveneers, Erik H. J. Danen
doaj   +1 more source

Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo

open access: yes, 2012
After activation, Langerhans cells (LC), a distinct subpopulation of epidermis-resident dendritic cells, migrate from skin to lymph nodes where they regulate the magnitude and quality of immune responses initiated by epicutaneously applied antigens ...
Feng, X.   +7 more
core   +1 more source

Spindle pole cohesion requires glycosylation-mediated localization of NuMA

open access: yesScientific Reports, 2017
Glycosylation is critical for the regulation of several cellular processes. One glycosylation pathway, the unusual O-linked β-N-acetylglucosamine glycosylation (O-GlcNAcylation) has been shown to be required for proper mitosis, likely through a subset of
Jérémy Magescas   +10 more
doaj   +1 more source

Roles of programmed death‐1 and muscle innate lymphoid cell‐derived interleukin 13 in sepsis‐induced intensive care unit‐acquired weakness

open access: yesJournal of Cachexia, Sarcopenia and Muscle
Background Intensive care unit‐acquired weakness (ICU‐AW) is a syndrome characterized by a long‐term muscle weakness often observed in sepsis‐surviving patients during the chronic phase.
Yuichi Akama   +12 more
doaj   +1 more source

Segregation of receptor-ligand complexes in cell adhesion zones: Phase diagrams and role of thermal membrane roughness

open access: yes, 2010
The adhesion zone of immune cells, the 'immunological synapse', exhibits characteristic domains of receptor-ligand complexes. The domain formation is likely caused by a length difference of the receptor-ligand complexes, and has been investigated in ...
Alberts B   +9 more
core   +1 more source

Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells

open access: yesNature Communications, 2017
Cancer cells can disrupt cell-to-cell junctions, thus allowing migration and metastasis. Here starting from a chemical screening, Ito et al. reconstitute a step-by-step mechanism linking microtubule depolymerization and epithelial cell junction ...
Shoko Ito   +6 more
doaj   +1 more source

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