Results 101 to 110 of about 11,890,652 (305)
For successful transplantation of Hematopoietic Stem cells (HSCs), it is quite necessary that efficient homing, engraftment and retention of HSC self-renewal capacity takes place, which is often restricted due to inadequate number of adult HSCs. Here, we
Anoushka Khanna+3 more
doaj +1 more source
E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells
The ability of carcinomas to invade and to metastasize largely depends on the degree of epithelial differentiation within the tumors, i.e., poorly differentiated being more invasive than well-differentiated carcinomas.
U. Frixen+5 more
semanticscholar +1 more source
Focal Adhesion-Independent Cell Migration.
Cell migration is central to a multitude of physiological processes, including embryonic development, immune surveillance, and wound healing, and deregulated migration is key to cancer dissemination.
E. Paluch, Irene M. Aspalter, M. Sixt
semanticscholar +1 more source
Activation of Src family kinases is an important event downstream of integrin adhesion signaling in many cell types. A particularly intriguing connection between an integrin and a Src family kinase was first discovered in platelets, where the selective ...
Stephan Huveneers, Erik H. J. Danen
doaj +1 more source
After activation, Langerhans cells (LC), a distinct subpopulation of epidermis-resident dendritic cells, migrate from skin to lymph nodes where they regulate the magnitude and quality of immune responses initiated by epicutaneously applied antigens ...
Feng, X.+7 more
core +1 more source
Spindle pole cohesion requires glycosylation-mediated localization of NuMA
Glycosylation is critical for the regulation of several cellular processes. One glycosylation pathway, the unusual O-linked β-N-acetylglucosamine glycosylation (O-GlcNAcylation) has been shown to be required for proper mitosis, likely through a subset of
Jérémy Magescas+10 more
doaj +1 more source
Background Intensive care unit‐acquired weakness (ICU‐AW) is a syndrome characterized by a long‐term muscle weakness often observed in sepsis‐surviving patients during the chronic phase.
Yuichi Akama+12 more
doaj +1 more source
The adhesion zone of immune cells, the 'immunological synapse', exhibits characteristic domains of receptor-ligand complexes. The domain formation is likely caused by a length difference of the receptor-ligand complexes, and has been investigated in ...
Alberts B+9 more
core +1 more source
Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells
Cancer cells can disrupt cell-to-cell junctions, thus allowing migration and metastasis. Here starting from a chemical screening, Ito et al. reconstitute a step-by-step mechanism linking microtubule depolymerization and epithelial cell junction ...
Shoko Ito+6 more
doaj +1 more source