Results 111 to 120 of about 5,944,904 (315)

Receptors of cell adhesion and cellular recognition /

, 1996
Volume 3 of Biomembranes covers receptors of cell adhesion and cellular recognition. Proteins in the plasma membrane of cells are heavily involved in processes of cell adhesion, but such proteins were not actually isolated and characterized until the mid-
Lee, A. G.
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Intermediate filament–membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strength [PDF]

, 2002
By tethering intermediate filaments (IFs) to sites of intercellular adhesion, desmosomes facilitate formation of a supercellular scaffold that imparts mechanical strength to a tissue.
Godsel, Lisa M., Hudson, TY, Green, Kathleen J., Kathleen J. Green, Gumbiner, BM, Hudson, Tracie Y., Kelsell, David P., Leigh, IM, Leigh, Irene M., Evangeline V. Amargo, Anne K. Mongiu, Huen, Arthur C., Leslie J. Bannon, Bannon, Leslie J., Mongiu, AK, David P. Kelsell, Kelsell, DP, Park, Jung K., Park, JK, Green, KJ, Huen, AC, Chen, XJ, Xuejun Chen, Bannon, LJ, Arthur C. Huen, Amargo, Evangeline V., Gumbiner, Barry M., Chen, Xuejun, Tracie Y. Hudson, Irene M. Leigh, Lisa M. Godsel, Barry M. Gumbiner, Mongiu, Anne K., Jung K. Park, Amargo, FV, Godsel, LM   +35 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cell Migration with Multiple Pseudopodia: Temporal and Spatial Sensing Models [PDF]

, 2013
Cell migration triggered by pseudopodia (or “false feet”) is the most used method of locomotion. A 3D finite element model of a cell migrating over a 2D substrate is proposed, with a particular focus on the mechanical aspects of the biological phenomenon.
ALLENA, Rachele
core   +1 more source

Roles of programmed death‐1 and muscle innate lymphoid cell‐derived interleukin 13 in sepsis‐induced intensive care unit‐acquired weakness

Journal of Cachexia, Sarcopenia and Muscle
Background Intensive care unit‐acquired weakness (ICU‐AW) is a syndrome characterized by a long‐term muscle weakness often observed in sepsis‐surviving patients during the chronic phase.
Yuichi Akama, Eun Jeong Park, Naoko Satoh‐Takayama, Atsushi Ito, Eiji Kawamoto, Arong Gaowa, Eri Matsuo, Satoshi Oikawa, Masafumi Saito, Shigeaki Inoue, Takayuki Akimoto, Kei Suzuki, Motomu Shimaoka   +12 more
doaj   +1 more source

The Interaction of Src Kinase with β3 Integrin Tails: A Potential Therapeutic Target in Thrombosis and Cancer

The Scientific World Journal, 2010
Activation of Src family kinases is an important event downstream of integrin adhesion signaling in many cell types. A particularly intriguing connection between an integrin and a Src family kinase was first discovered in platelets, where the selective ...
Stephan Huveneers, Erik H. J. Danen
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown [PDF]

, 2010
Background: An inducible release of soluble junctional adhesion molecule-A (sJAM-A) under pro-inflammatory conditions was described in cultured non-CNS endothelial cells (EC) and increased sJAM-A serum levels were found to indicate inflammation in non ...
Romero, Ignacio, Deiß Annika, Deiß, Annika, Buttmann, Mathias, Weksler Babette, Rieckmann, Peter, Ignacio Romero, Mathias Buttmann, Prochaska, Jürgen, Couraud, Pierre-Olivier, Jürgen Prochaska, Haarmann, Axel, Peter Rieckmann, Buttmann Mathias, Weksler, Babette, Axel Haarmann, Stoll, Guido, Najbauer, Joseph, Pierre-Olivier Couraud, Annika Deiss, Couraud Pierre-Olivier, Prochaska, Juergen, Stoll Guido, Guido Stoll, Förch, Christian, Romero Ignacio, Foerch, Christian, Prochaska Jürgen, Christian Foerch, Rieckmann Peter, Babette Weksler, Foerch Christian, Haarmann Axel   +32 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source