Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Synaptic cell adhesion molecule <i>Cdh6</i> identifies a class of sensory neurons with novel functions in colonic motility. [PDF]
Gomez-Frittelli J+8 more
europepmc +1 more source
Neural cell adhesion molecules.
Adhesion molecules are expressed on the surface of various cells and establish cell-cell interaction, playing important roles in development, inflammatory reaction, immune response, and tissue regeneration. Neural adhesion molecules, found on neurons or glial surfaces, are involved in the migration of neurons, neurite formation, myelination, and ...
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RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav+5 more
wiley +1 more source
Basal cell adhesion molecule (BCAM) promotes mesothelial-to-mesenchymal transition and tumor angiogenesis through paracrine signaling. [PDF]
Sivakumar S+14 more
europepmc +1 more source
Natural ligands of the B cell adhesion molecule CD22 beta can be masked by 9-O-acetylation of sialic acids. [PDF]
Eric R. Sjoberg+3 more
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Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers+3 more
wiley +1 more source
The cell adhesion molecule CD44 acts as a modulator of 5-HT7 receptor functions. [PDF]
Borsdorf S+9 more
europepmc +1 more source
Role of endothelial leukocyte adhesion molecule-1 and platelet-activating factor in neutrophil adherence to IL-1-prestimulated endothelial cells. Endothelial leukocyte adhesion molecule-1-mediated CD18 activation. [PDF]
Taco W. Kuijpers+4 more
openalex +1 more source