Results 211 to 220 of about 1,169,770 (361)

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

Advanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer, Sebastian Krämer, Ngoc Anh Hoang, Doreen Sittig, Isabella Metelmann, Uta‐Carolin Pietsch, Sebastian N. Stehr, Sonja Kallendrusch, Tobias Piegeler   +8 more
wiley   +1 more source

The cell adhesion molecule CD44 acts as a modulator of 5-HT7 receptor functions. [PDF]

Cell Commun Signal
Borsdorf S, Zeug A, Wu Y, Mitroshina E, Vedunova M, Gaitonde SA, Bouvier M, Wehr MC, Labus J, Ponimaskin E.   +9 more
europepmc   +1 more source

The Neural Cell Adhesion Molecule NCAM Is an Alternative Signaling Receptor for GDNF Family Ligands

Cell, 2003
G. Paratcha, F. Ledda, C. Ibáñez
semanticscholar   +1 more source

Circulating intercellular adhesion molecule-1 (ICAM-1), E-selectin and vascular cell adhesion molecule-1 (VCAM-1) in human malignancies

, 1993
Rosamonde E. Banks, AJ Gearing, IK Hemingway, DR Norfolk, Timothy Perren, P Selby   +5 more
openalex   +2 more sources

Neural Cell Adhesion Molecule [PDF]

, 2018
S. Holdenrieder, P. Stieber
openaire   +2 more sources

Loss of Stat3 in Prx1+ Progenitors Impairs Molar Root Development

Advanced Biology, EarlyView.
Stat3 critically regulates mandibular first molar and alveolar bone morphogenesis. Conditional ablation of Stat3 disrupts the osteogenic capacity of Prx1+ mesenchymal progenitors, as evidenced across in vivo and in vitro models. Abstract Signal Transducer and Activator of Transcription 3 (Stat3) acts as a central transcriptional modulator coordinating ...
Xin Feng, Wangyu Luo, Yichen Yao, Lichieh Lin, Laiting Chan, Jiarui Lu, Zijing Huang, Jingyi Feng, Le Zhao, Xiaolei Zhang, Liu Yang   +10 more
wiley   +1 more source

Basal cell adhesion molecule (BCAM) promotes mesothelial-to-mesenchymal transition and tumor angiogenesis through paracrine signaling. [PDF]

Cell Commun Signal
Sivakumar S, Lieber S, Dietze R, Beutgen VM, Sutor EC, Heidemann S, Finkernagel F, Teply-Szymanski J, Nist A, Stiewe T, Roth K, Reinartz S, Graumann J, Müller-Brüsselbach S, Müller R.   +14 more
europepmc   +1 more source

Dtrk, a Drosophila gene related to the trk family of neurotrophin receptors, encodes a novel class of neural cell adhesion molecule.

, 1992
Diego Pulido, Sonsoles Campuzano, Toshiaki Koda, Juan Modolell, Mariano Barbacid   +4 more
openalex   +1 more source

Expression of the neural cell adhesion molecule and polysialic acid during early mouse embryogenesis [PDF]

, 1994
Rainer Probstmeier, A. Bilz, Jürgen Schneider‐Schaulies   +2 more
openalex   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source