Results 251 to 260 of about 639,519 (352)

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer   +7 more
wiley   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

open access: yesAdvanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram   +5 more
wiley   +1 more source

The cell adhesion molecule CD44 acts as a modulator of 5-HT7 receptor functions. [PDF]

open access: yesCell Commun Signal
Borsdorf S   +9 more
europepmc   +1 more source

High‐Concentration Mesogen‐Assisted Exfoliation of Low‐Dimensional Nanomaterials for Achieving Ultralow‐Temperature Actuations of Liquid Crystal Elastomers

open access: yesAdvanced Functional Materials, EarlyView.
Most matter is nominally frozen in the polar regions or space, and liquid crystal materials are no exception. Consequently, soft actuators, including liquid crystal elastomers (LCEs), are inoperative under such extreme cold in response to stimuli, as their motion relies on mechanical deformation.
Hyeonseong Kim   +5 more
wiley   +1 more source

Synaptic cell adhesion molecule <i>Cdh6</i> identifies a class of sensory neurons with novel functions in colonic motility. [PDF]

open access: yesElife
Gomez-Frittelli J   +8 more
europepmc   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

open access: yesAdvanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt   +2 more
wiley   +1 more source

An antibody-drug conjugate for endometrioid carcinoma based on the expression of cell adhesion molecule 1. [PDF]

open access: yesMol Cell Oncol
Hagiyama M   +7 more
europepmc   +1 more source

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

open access: yesAdvanced Functional Materials, EarlyView.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz   +7 more
wiley   +1 more source

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