Thioredoxin1 downregulates oxidized low-density lipoprotein-induced adhesion molecule expression via Smad3 protein. [PDF]
PLoS ONE, 2013 Atherosclerosis is a chronic inflammation disease that is initiated by endothelial cell injury. Oxidized low-density lipoprotein (ox-LDL) is directly associated with chronic vascular inflammation. To understand whether thioredoxin1 (Trx1) participates in
Beidong Chen +3 more
doaj +1 more source
Pcdh11x controls target specification of mossy fiber sprouting
Frontiers in Neuroscience, 2022 Circuit formation is a defining characteristic of the developing brain. However, multiple lines of evidence suggest that circuit formation can also take place in adults, the mechanisms of which remain poorly understood. Here, we investigated the epilepsy-
Wenshu Luo +6 more
doaj +1 more source
Cultured microvascular endothelial cells derived from the bovine corpus luteum possess NCAM-140 [PDF]
, 1992 Previously, five phenotypically different, stable types of microvascular endothelial cells (MVE) were isolated from the bovine corpus and cultured successfully. We found that three out of these five types of MVE express the neural cell adhesion molecule (
Caney +11 more
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Putative cell adhesion membrane protein Vstm5 regulates neuronal morphology and migration in the central nervous system [PDF]
, 2016 During brain development, dynamic changes in neuronal membranes perform critical roles in neuronal morphogenesis and migration to create functional neural circuits.
Ko, Kwang Woo +5 more
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Cell adhesion molecules and exercise
Journal of Inflammation Research, 2018 An extensive systematic review was undertaken in the current literature in order to explore the role of different types and intensities of exercise in cell adhesion molecules (CAMs), one of the markers of vascular inflammation, endothelial dysfunction, and atherosclerosis.Twenty-eight qualifying studies were extensively reviewed to examine the effects ...
Yunsuk Koh, Jinkyung Park
openaire +6 more sources
CD44 cell adhesion molecules [PDF]
Molecular Pathology, 1999 The CD44 proteins form a ubiquitously expressed family of cell surface adhesion molecules involved in cell-cell and cell-matrix interactions. The multiple protein isoforms are encoded by a single gene by alternative splicing and are further modified by a range of post-translational modifications. CD44 proteins are single chain molecules comprising an N-
David Tarin +2 more
openaire +3 more sources
Urokinase does not upregulate the vascular endothelial cell–mediated inflammatory response [PDF]
, 1997 Purpose: Urokinase is used clinically for thrombolysis, but little is known of its direct effect on vascular endothelial cells. The following experiments were preformed to assess the in vitro effects of urokinase on vascular endothelial cell growth ...
Gifford, Robert R.M. +2 more
core +1 more source
Site-Specific Effects of PECAM-1 on Atherosclerosis in LDL Receptor-Deficient Mice [PDF]
, 2008 Objective—Atherosclerosis is a vascular disease that involves lesion formation at sites of disturbed flow under the influence of genetic and environmental factors.
Arora, Shikha +9 more
core +2 more sources
The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules [PDF]
, 2016 Multicellular organisms rely on cell adhesion molecules to coordinate cell–cell interactions, and to provide navigational cues during tissue formation.
Davies, Shireen-Anne +7 more
core +2 more sources
Flavopiridol Protects Against Inflammation by Attenuating Leukocyte-Endothelial Interaction via Inhibition of Cyclin-Dependent Kinase 9 [PDF]
, 2011 Objective: The cyclin-dependent kinase (CDK) inhibitor flavopiridol is currently being tested in clinical trials as anticancer drug. Beyond its cell death–inducing action, we hypothesized that flavopiridol affects inflammatory processes.
Berberich, Nina +11 more
core +1 more source