Results 21 to 30 of about 583,703 (360)
Pcdh11x controls target specification of mossy fiber sprouting
Frontiers in Neuroscience, 2022 Circuit formation is a defining characteristic of the developing brain. However, multiple lines of evidence suggest that circuit formation can also take place in adults, the mechanisms of which remain poorly understood. Here, we investigated the epilepsy-
Wenshu Luo +6 more
doaj +1 more source
Clinics, 2018 OBJECTIVES: Inflammatory molecules play a role in the development of atherosclerosis, which is the primary origin of cardiovascular disorders. However, to the best of our knowledge, no study has attempted to investigate the relationship between these ...
Jéssica Cavalcante dos Santos +14 more
doaj +1 more source
Thioredoxin1 downregulates oxidized low-density lipoprotein-induced adhesion molecule expression via Smad3 protein. [PDF]
PLoS ONE, 2013 Atherosclerosis is a chronic inflammation disease that is initiated by endothelial cell injury. Oxidized low-density lipoprotein (ox-LDL) is directly associated with chronic vascular inflammation. To understand whether thioredoxin1 (Trx1) participates in
Beidong Chen +3 more
doaj +1 more source
Cell adhesion molecules and exercise
Journal of Inflammation Research, 2018 An extensive systematic review was undertaken in the current literature in order to explore the role of different types and intensities of exercise in cell adhesion molecules (CAMs), one of the markers of vascular inflammation, endothelial dysfunction, and atherosclerosis.Twenty-eight qualifying studies were extensively reviewed to examine the effects ...
Yunsuk Koh, Jinkyung Park
openaire +6 more sources
Site-Specific Effects of PECAM-1 on Atherosclerosis in LDL Receptor-Deficient Mice [PDF]
, 2008 Objective—Atherosclerosis is a vascular disease that involves lesion formation at sites of disturbed flow under the influence of genetic and environmental factors.
Arora, Shikha +9 more
core +2 more sources
CD44 cell adhesion molecules [PDF]
Molecular Pathology, 1999 The CD44 proteins form a ubiquitously expressed family of cell surface adhesion molecules involved in cell-cell and cell-matrix interactions. The multiple protein isoforms are encoded by a single gene by alternative splicing and are further modified by a range of post-translational modifications. CD44 proteins are single chain molecules comprising an N-
David Tarin +2 more
openaire +3 more sources
Flavopiridol Protects Against Inflammation by Attenuating Leukocyte-Endothelial Interaction via Inhibition of Cyclin-Dependent Kinase 9 [PDF]
, 2011 Objective: The cyclin-dependent kinase (CDK) inhibitor flavopiridol is currently being tested in clinical trials as anticancer drug. Beyond its cell death–inducing action, we hypothesized that flavopiridol affects inflammatory processes.
Berberich, Nina +11 more
core +1 more source
Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the β1 integrin-RACK1 axis. [PDF]
, 2012 Trop-2 is a transmembrane glycoprotein upregulated in several human carcinomas, including prostate cancer (PrCa). Trop-2 has been suggested to regulate cell-cell adhesion, given its high homology with the other member of the Trop family, Trop-1/EpCAM ...
Alberti, Saverio +3 more
core +2 more sources
Expression of the neural cell adhesion molecule NCAM in endocrine cells [PDF]
, 1989 We examined the expression of the neural cell adhesion molecule NCAM in a number of endocrine tissues of adult rat and in an endocrine tumor cell line. NCAM was found by immunoelectron microscopy to be present on the surface of all endocrine cells in the
Aletsee-Ufrecht, M. C. +3 more
core +1 more source
Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule. [PDF]
, 1989 Neural cell adhesion molecule (N-CAM) is a membrane glycoprotein expressed on neural and muscle tissues that is involved in homotypic adhesive interactions.
Bindl, J +3 more
core +1 more source