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Cell Adhesion Molecules: An Overview
Cancer Investigation, 1998Considerable basic research, mostly in the past 20 years, has elicited greatly increased knowledge concerning the structure and function of cell adhesion molecules. Scores of individual adhesion molecules have been identified and categorized as to major structural features, ligands recognized, and pattern of expression.
Jacquelyn Joseph-Silverstein +1 more
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2008
Cell adhesion molecules, also termed cell adhesion receptors, are one of three classes of macromolecules – along with extracellular matrix molecules and adhesion plaque proteins – that mediate cell adhesion, an activity which is critical for the commencement and maintenance of the three-dimensional structure and normal function of tissues.1,2 Cell ...
Philip T. Cagle, Timothy Craig Allen
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Cell adhesion molecules, also termed cell adhesion receptors, are one of three classes of macromolecules – along with extracellular matrix molecules and adhesion plaque proteins – that mediate cell adhesion, an activity which is critical for the commencement and maintenance of the three-dimensional structure and normal function of tissues.1,2 Cell ...
Philip T. Cagle, Timothy Craig Allen
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Cell adhesion molecules and sleep
Neuroscience Research, 2017Cell adhesion molecules (CAMs) play essential roles in the central nervous system, where some families are involved in synaptic development and function. These synaptic adhesion molecules (SAMs) are involved in the regulation of synaptic plasticity, and the formation of neuronal networks. Recent findings from studies examining the consequences of sleep
Emma K. O’Callaghan +2 more
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Cell adhesion molecules at the synapse
Frontiers in Bioscience, 2006Synapses are specialized intercellular junctions whose specificity and plasticity provide the structural and functional basis for the formation and maintenance of the complex neural network in the brain. The number, location, and type of synapses formed are well controlled, since synaptic circuits are formed in a highly reproducible way.
Kimberly Gerrow, Alaa El-Husseini
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1995
Adhesion molecules enable cell-cell interactions necessary for their communication and cooperation.
H.-Harald Sedlacek, Tarik Möröy
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Adhesion molecules enable cell-cell interactions necessary for their communication and cooperation.
H.-Harald Sedlacek, Tarik Möröy
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Cell adhesion molecules in vasculitis
Current Opinion in Rheumatology, 1997Activation of the vascular endothelium by several different stimuli plays a crucial role in the initiation, localization, and propagation of vascular injury. In vitro studies have demonstrated that activation of cultured vascular endothelial cells renders them hyperadhesive for leukocytes.
C. G. M. Kallenberg +1 more
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2019
To orchestrate development and maintain tissue homeostasis, multicellular organisms have evolved a large number of cell adhesion molecules (CAMs). There are four major classes of CAMs: the immunoglobulin superfamily (IgSF), the cadherins, the integrins and the selectins.
Xia-Jing Tong, Yan Zou
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To orchestrate development and maintain tissue homeostasis, multicellular organisms have evolved a large number of cell adhesion molecules (CAMs). There are four major classes of CAMs: the immunoglobulin superfamily (IgSF), the cadherins, the integrins and the selectins.
Xia-Jing Tong, Yan Zou
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Cell adhesion molecules and cancer
Current Opinion in Oncology, 1992Cell adhesion molecules are complex protein and carbohydrate molecules of many different types found on the surfaces of all cells. They are important in many aspects of cell biology including development, differentiation, and motility. These processes are frequently disturbed in cancer and recent work has demonstrated that disturbances in cell adhesion
Jonathan Fawcett, Adrian L. Harris
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Glycosyltransferases as cell adhesion molecules
Current Opinion in Cell Biology, 1993Specific glycosyltransferases are believed to be present on the cell surface, where they may function as cell adhesion molecules by binding oligosaccharide substrates on adjacent cell surfaces or in the extracellular matrix. The best studied of these is beta 1,4-galactosyltransferase, which mediates sperm binding to the egg coat and selected cell ...
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