Results 71 to 80 of about 574,774 (360)

Expression changes of nerve cell adhesion molecules L1 and semaphorin 3A after peripheral nerve injury

Neural Regeneration Research, 2016
The expression of nerve cell adhesion molecule L1 in the neuronal growth cone of the central nervous system is strongly associated with the direction of growth of the axon, but its role in the regeneration of the peripheral nerve is still unknown.
Qian-ru He, Meng Cong, Qing-zhong Chen, Ya-feng Sheng, Jian Li, Qi Zhang, Fei Ding, Yan-pei Gong   +7 more
doaj   +1 more source

The mitochondrial outer membrane protein SYNJ2BP interacts with the cell adhesion molecule TMIGD1 and can recruit it to mitochondria

BMC Molecular and Cell Biology, 2020
Background Transmembrane and immunoglobulin domain-containing protein 1 (TMIGD1) is a recently identified cell adhesion molecule which is predominantly expressed by epithelial cells of the intestine and the kidney. Its expression is downregulated in both
Christian Hartmann, Ysabel Alessa Schwietzer, Daniel Kummer, Nils Kirschnick, Esther Hoppe, Eva-Maria Thüring, Mark Glaesner-Ebnet, Frauke Brinkmann, Volker Gerke, Stefan Reuter, Masanori Nakayama, Klaus Ebnet   +11 more
doaj   +1 more source

Attenuation of leukocyte sequestration by selective blockade of PECAM-1 or VCAM-1 in murine endotoxemia [PDF]

, 2004
Background: Molecular mechanisms regulating leukocyte sequestration into the tissue during endotoxemia and/or sepsis are still poorly understood. This in vivo study investigates the biological role of murine PECAM-1 and VCAM-1 for leukocyte sequestration
Chosay JG, Chosay JG, Christofidou-Solomidou M, D. Nolte, Dinarello CA, Essani NA, Hahne M, Hoffmann JN, Jin HK, K. Messmer, K.-D. Wolff, Khan BV, Kuebler WM, Kunkel EJ, Muchamuel T, Neumann B, Nolte D, Nolte D, Nolte D, Orosz CG, Piedboeuf B, Vaporciyan AA, Vestweber D, W.A. Muller, W.M. Kuebler, Zeintl H   +25 more
core   +1 more source

Vascular Cell Adhesion Molecule-1 Is a Key Adhesion Molecule in Melanoma Cell Adhesion to the Leptomeninges [PDF]

Laboratory Investigation, 2002
Leptomeningeal metastases occur in up to 8% of patients with systemic malignancies and have a poor prognosis. A better understanding of the pathophysiologic processes underlying leptomeningeal metastases is needed for more effective treatment strategies.
Jaap-Jan Zwaginga, Martin J.B. Taphoorn, J. C. Reijneveld, Laurien H. Ulfman, Dieta Brandsma, Martijn F.B.G. Gebbink, Hetty C. de Boer, Hetty C. de Boer, Emile E. Voest   +8 more
openaire   +3 more sources

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Cryopreservation-Induced Nonattachment of Human Hepatocytes: Role of Adhesion Molecules

Cell Transplantation, 2007
Good quality cryopreserved human hepatocytes are becoming an important source for clinical hepatocyte transplantation. However, the process of cryopreservation leads to both structural and functional impairment of hepatocytes.
Claire Terry, Robin D. Hughes, Ragai R. Mitry, Sharon C. Lehec, Anil Dhawan   +4 more
doaj   +1 more source

Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown [PDF]

, 2010
Background: An inducible release of soluble junctional adhesion molecule-A (sJAM-A) under pro-inflammatory conditions was described in cultured non-CNS endothelial cells (EC) and increased sJAM-A serum levels were found to indicate inflammation in non ...
Buttmann, Mathias, Couraud, Pierre-Olivier, Deiß, Annika, Foerch, Christian, Haarmann, Axel, Najbauer, Joseph, Prochaska, Jürgen, Rieckmann, Peter, Romero, Ignacio, Stoll, Guido, Weksler, Babette   +10 more
core   +5 more sources

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

A Comparison of Endothelial Cell-Selective Adhesion Molecule and von Willebrand Factor Expression in Breast Cancer Growth and Metastasis

Middle East Journal of Cancer, 2018
Background: Angiogenesis is the process of new blood vessels formation that contribute to tumor growth and metastasis. Endothelial cell-selective adhesion molecule is one of the proteins that expresses in vascular endothelial cells.
M Husni Cangara, Mochammad Hatta, Upik A Miskad, Syarifuddin Wahid   +3 more
doaj