Results 141 to 150 of about 456,144 (261)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Signal regulating proteins (SIRPs) participate in sarcoidosis granuloma formation by promoting immune cell aggregation. [PDF]

Respir Res
Judson MA, Julian MW, Foulke L, Panicker S, Arker SH, Feustel PJ, Parry G, Bicer S, Crouser ED.   +8 more
europepmc   +1 more source

TJP1 Contributes to Tumor Progression through Supporting Cell-Cell Aggregation and Communicating with Tumor Microenvironment in Leiomyosarcoma. [PDF]

Mol Cells, 2021
Lee EY, Kim M, Choi BK, Kim DH, Choi I, You HJ.   +5 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Quorum sensing regulates a polysaccharide biosynthesis gene to control cell aggregation in <i>Paracoccus denitrificans</i>. [PDF]

ISME Commun
Morinaga K, Takahashi K, Nagasawa R, Tao W, Sugimoto S, Obana N, Nomura N, Utada AS, Toyofuku M.   +8 more
europepmc   +1 more source

Low-Cost Devices for Three-Dimensional Cell Aggregation, Real-Time Monitoring Microscopy, Microfluidic Immunostaining, and Deconvolution Analysis. [PDF]

Bioengineering (Basel), 2022
Struber A, Auer G, Fischlechner M, Wickstrom C, Reiter L, Lutsch E, Simon-Nobbe B, Marozin S, Lepperdinger G.   +8 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Changes in Cell Aggregation in <i>Arabidopsis thaliana</i> Suspension Culture Following Knockout of GAUT Gene Family Members. [PDF]

Plants (Basel)
Frankevich TA, Permyakova NV, Sidorchuk YV, Deineko EV.   +3 more
europepmc   +1 more source

Lipid tethering of breast tumor cells reduces cell aggregation during mammosphere formation. [PDF]

Sci Rep, 2021
Bhandary L, Bailey PC, Chang KT, Underwood KF, Lee CJ, Whipple RA, Jewell CM, Ory E, Thompson KN, Ju JA, Mathias TM, Pratt SJP, Vitolo MI, Martin SS.   +13 more
europepmc   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source