Results 101 to 110 of about 1,710,556 (364)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Exploring the application value of ultrasound in animal studies of stem cell therapy for intrauterine adhesions

Scientific Reports
Endometrial damage leads to intrauterine adhesions (IUA), significantly impairing endometrial receptivity and fertility. Stem cell therapies, particularly umbilical cord mesenchymal stem cell (UC-MSCs), have shown promise in regenerating damaged ...
Siqi Guo, Wencong Li, Xiaoran Chen, Meijuan Liu   +3 more
doaj   +1 more source

Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool. [PDF]

, 2008
Mesenchymal stem cells (MSCs) from adult somatic tissues may differentiate in vitro and in vivo into multiple mesodermal tissues including bone, cartilage, adipose tissue, tendon, ligament or even muscle. MSCs preferentially home to damaged tissues where
García-Castro, J, Madrenas, J, Menendez, P, Pérez-Simón, JA, Rodriguez, R, Trigueros, C   +5 more
core  

The light and shadow of senescence and inflammation in cardiovascular pathology and regenerative medicine [PDF]

, 2017
Recent epidemiologic studies evidence a dramatic increase of cardiovascular diseases, especially associated with the aging of the world population. During aging, the progressive impairment of the cardiovascular functions results from the compromised ...
Cavarretta, Elena, Dal Sasso, Eleonora, Forte, Maurizio, Frati, Giacomo, Gerosa, Gino, Iop, Laura, Palmerio, Silvia, Peruzzi, Mariangela, Schirone, Leonardo, Sciarretta, Sebastiano   +9 more
core   +4 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Effect of stem cells combined with a polymer/ceramic membrane on osteoporotic bone repair

Brazilian Oral Research
Cell therapy associated with guided bone regeneration (GBR) can be used to treat bone defects under challenging conditions such as osteoporosis.
Adriana Luisa Goncalves ALMEIDA, Gileade Pereira FREITAS, Helena Bacha LOPES, Rossano GIMENES, Selma SIESSERE, Luiz Gustavo SOUSA, Marcio Mateus BELOTI, Adalberto Luiz ROSA   +7 more
doaj   +1 more source

Intraoral Bone Regeneration Using Stem Cells - What a Clinician Needs to Know: Based on a 15-Year MEDLINE Search

Frontiers in Dentistry, 2021
The choice of an appropriate autogenous source of stem cells has not been adequately addressed especially for intraoral bone regeneration. The current review aims to assess the clinical success of various human stem cells in oral bone regeneration ...
Vanshika Jain, Deborah Sybil, Shubhangi Premchandani, Meenakshi Krishna, Sanjay Singh   +4 more
doaj  

Clinical Protocol to Prevent Thrombogenic Effect of Liver-Derived Mesenchymal Cells for Cell-Based Therapies

Cells, 2019
The efficacy of mesenchymal stem cell infusion is currently tested in numerous clinical trials. However, therapy-induced thrombotic consequences have been reported in several patients.
Louise Coppin, Mustapha Najimi, Julie Bodart, Marie-Sophie Rouchon, Patrick van der Smissen, Stéphane Eeckhoudt, Géraldine Dahlqvist, Diego Castanares-Zapatero, Mina Komuta, Sanne L. Brouns, Constance C. Baaten, Johan W. M. Heemskerk, Sandrine Horman, Nathalie Belmonte, Etienne Sokal, Xavier Stéphenne   +15 more
doaj   +1 more source

95 MAGE-A1 protein expression pattern in > 5,000 tumor and healthy tissue samples: Validation of MAGE-A1 as an ideal target for TCR-based cell therapy [PDF]

, 2021
Jennifer D. Oduro, Ronald Simon, Natalia Gorbokon, Christoph Fraune, Julia Bluhm, Vivian Scheuplein, Elisa Kieback, Matthias Obenaus, Thomas Blankenstein, Eugen Leo   +9 more
openalex   +1 more source

Chemotherapy-Response Monitoring of Breast Cancer Patients Using Quantitative Ultrasound-Based Intra-Tumour Heterogeneities [PDF]

, 2017
© 2017 The Author(s). Anti-cancer therapies including chemotherapy aim to induce tumour cell death. Cell death introduces alterations in cell morphology and tissue micro-structures that cause measurable changes in tissue echogenicity.
A Ahmed, A Guimond, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, B Banihashemi, B Fisher, B Ganeshan, BS Garra, BS Pio, BT Hennessy, C-P Chou, D Sethi, DA Mankoff, EJ Feleppa, EJ Feleppa, F Tixier, FJ Esteva, FL Lizzi, FT D’Astous, G Berger, G Minckwitz von, GJ Czarnota, GJ Czarnota, GN Hortobagyi, H Haibo, H Tadayyon, H Tadayyon, H Tadayyon, HC Kim, HM Kuerer, II Wistuba, J Czernin, JB Nikas, JPB O’Connor, K Brindle, K Sikora, K Suzuki, KA Wear, KM Brindle, KN Ogston, L Sannachi, LX Yao, M Dowsett, M Vaidya, MF Insana, ML Oelze, ML Oelze, N Duric, O Falou, O Falou, QH Huang, R Tiling, RM Haralick, RM Vlad, RM Vlad, SH Giordano, SH Giordano, SJ Cleator, SM Scholl, T Cover, TJ Larkin, U McDermott, V Goh, V Guarneri, X Li, Y Labyed   +70 more
core   +2 more sources