Results 131 to 140 of about 1,710,556 (364)

Label-free high-throughput photoacoustic tomography of suspected circulating melanoma tumor cells in patients in vivo [PDF]

, 2020
Significance: Detection and characterization of circulating tumor cells (CTCs), a key determinant of metastasis, are critical for determining risk of disease progression, understanding metastatic pathways, and facilitating early clinical intervention.
Cornelius, Lynn A., Hai, Pengfei, Li, Yang, Qu, Yuan, Shmuylovich, Leonid, Wang, Lihong V., Zhu, Liren   +6 more
core   +1 more source

Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer. [PDF]

, 2012
Thus, we evaluated the immunofluorescence pattern of TRAIL-receptors and E-cadherin to assess the fraction of membrane-bound TRAIL-receptors in 231 selected patients with early-stage CRC undergoing surgical treatment only.
De Toni, Enrico N., Gallmeier, Eike, Gerbes, Alexander L., Göke, Burkhard, Hermeking, Heiko, Horst, David, Jackstadt, Rene, Jung, Andreas, Kirchner, Thomas, Kriegl, Lydia, Rizzani, Antonia   +10 more
core   +3 more sources

Omental grafting: a cell‐based therapy for blood vessel repair

Journal of Tissue Engineering and Regenerative Medicine, 2013
Clinicians regularly transplant omental pedicles to repair a wide variety of injured tissues, but the basic mechanism underlying this efficacious procedure is not understood.
Elaine L. Shelton, S. Poole, J. Reese, D. Bader   +3 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

AlPc/ZnPc-based oncological photodynamic therapy for a selective eradication of leukemic cells from ovarian tissue

, 2021
Saeid Moghassemi, Arezoo Dadashzadeh, Paulo Eduardo Narcizo de Souza, Ricardo Bentes Azevedo, Christiani A. Amorim   +4 more
openalex   +2 more sources

Sustained gene expression in the retina by improved episomal vectors [PDF]

, 2014
Gene and cellular therapies are nowadays part of therapeutic strategies for the treatment of diverse pathologies. The drawbacks associated with gene therapy-low levels of transgene expression, vector loss during mitosis, and gene silencing-need to be ...
Ana V. Oliveira, Conley S.M., Davis A.A., Gabriela A. Silva, Reinisalo M., Rudolf Haase, Sofia M. Calado, Susana Machado   +7 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Current landscape of clinical use of ex vivo expanded natural killer cells for cancer therapy [PDF]

Einstein (São Paulo)
Natural Killer cells are immune leukocytes required for responses against tumor cells and virus-infected cells. In the last decade, natural killer cells have emerged as promising tools in cancer therapy, and clinical studies on patients treated with ...
Júlia Teixeira Cottas de Azevedo, Juliana Aparecida Preto de Godoy, Cláudia de Souza, Micheli Severo Sielski, Larissa Leggieri Coa, Augusto Barbosa Júnior, Lucila Nassif Kerbauy, Andrea Tiemi Kondo, Oswaldo Keith Okamoto, Nelson Hamerschlak, José Mauro Kutner, Raquel de Melo Alves Paiva   +11 more
doaj   +1 more source

Tissue Engineering and Cell-Based Therapies for Fractures and Bone Defects [PDF]

, 2018
Jose Perez, Dimitrios Kouroupis, Deborah J. Li, Thomas M. Best, Lee D. Kaplan, Diego Correa   +5 more
openalex   +1 more source

Microvesicles as vehicles for tissue regeneration: Changing of the guards [PDF]

, 2016
Purpose of Review: Microvesicles (MVs) have been recognised as mediators of stem cell function, enabling and guiding their regenerative effects. Recent Findings: MVs constitute one unique size class of extracellular vesicles (EVs) directly shed from ...
Davies, R. Wayne, Panagiotou, Nikolaos, Selman, Colin, Shiels, Paul G.   +3 more
core   +1 more source