Results 251 to 260 of about 1,710,556 (364)
Albumin Nanoparticles as Multifunctional Carriers for Advanced Therapeutics. [PDF]
Konopska B +7 more
europepmc +1 more source
New perspectives of tissue remodelling with neural stem and progenitor cell-based therapies
Chiara Cossetti +4 more
openalex +2 more sources
Tissue Engineering Approaches to Cell-Based Type 1 Diabetes Therapy
Luke D. Amer, M. Mahoney, S. Bryant
semanticscholar +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Mesenchymal stem cell-based therapy.
Vaibhav Mundra +2 more
semanticscholar +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Tissue regenerative medicine: Clinical advances, challenges, and opportunities. [PDF]
Badawy S +12 more
europepmc +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source

