Results 251 to 260 of about 1,710,556 (364)

Albumin Nanoparticles as Multifunctional Carriers for Advanced Therapeutics. [PDF]

open access: yesPharmaceutics
Konopska B   +7 more
europepmc   +1 more source

New perspectives of tissue remodelling with neural stem and progenitor cell-based therapies

open access: green, 2012
Chiara Cossetti   +4 more
openalex   +2 more sources

Tissue Engineering Approaches to Cell-Based Type 1 Diabetes Therapy

open access: yesTissue engineering. Part B, Reviews, 2014
Luke D. Amer, M. Mahoney, S. Bryant
semanticscholar   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Mesenchymal stem cell-based therapy.

open access: yesMolecular Pharmaceutics, 2013
Vaibhav Mundra   +2 more
semanticscholar   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Tissue regenerative medicine: Clinical advances, challenges, and opportunities. [PDF]

open access: yesAPL Bioeng
Badawy S   +12 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

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