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Multiple Sclerosis: Pathogenesis, Symptoms, Diagnoses and Cell-Based Therapy
Cell journal, 2016Multiple sclerosis (MS) is a chronic inflammatory disease characterized by central nervous system (CNS) lesions that can lead to severe physical or cognitive disability as well as neurological defects. Although the etiology and pathogenesis of MS remains
N. Ghasemi, S. Razavi, E. Nikzad
semanticscholar +1 more source
2015
The regulatory environment for cell- and tissue-based therapeutic products and gene therapy products is rapidly evolving and drug regulatory agencies are working towards establishing a risk-based system in the regulatory framework. Similarly in Singapore, a risk-based tiered approach has been applied whereby clinical trials and product licence of high ...
Choon Wee, Goh +3 more
openaire +2 more sources
The regulatory environment for cell- and tissue-based therapeutic products and gene therapy products is rapidly evolving and drug regulatory agencies are working towards establishing a risk-based system in the regulatory framework. Similarly in Singapore, a risk-based tiered approach has been applied whereby clinical trials and product licence of high ...
Choon Wee, Goh +3 more
openaire +2 more sources
Regulatory Framework for Cell and Tissue Based Therapies in Europe
2016Whereas some basic therapies based on tissues and cells have been in clinical use for years, advances in regenerative medicine present new challenges and new types of products for regulation. This article focuses on cell therapies which can be classified as medicinal products across the European Union.
Gudrun Tiedemann, Sebastian Sethe
openaire +1 more source
Regulatory Frameworks for Cell and Tissue Based Therapies in Europe and the USA
2010Whereas some basic therapies based on tissues and cells have been in clinical use for years, regulatory regimes applying to such applications have recently been revised and extended in Europe and in the US. Moreover, advances in regenerative medicine present new challenges and new types of products for regulation.
Gudrun Tiedemann, Sebastian Sethe
openaire +1 more source
Transplantation
Background. Mild histologic lesions of tubulo-interstitial inflammation could represent a “response-to-wounding” rather than allorecognition. Tissue gene expression may complement histopathology for T-cell-mediated rejection (TCMR) diagnostics. Methods.
Dhiren, Kumar +12 more
openaire +2 more sources
Background. Mild histologic lesions of tubulo-interstitial inflammation could represent a “response-to-wounding” rather than allorecognition. Tissue gene expression may complement histopathology for T-cell-mediated rejection (TCMR) diagnostics. Methods.
Dhiren, Kumar +12 more
openaire +2 more sources
Ischemic preconditioning for cell-based therapy and tissue engineering.
Pharmacology and Therapeutics, 2014S. Hsiao +3 more
semanticscholar +1 more source
Cell- and tissue-based therapies for lung disease
2020Jeffrey A. Whitsett +3 more
openaire +1 more source

