Results 31 to 40 of about 1,710,556 (364)

Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy [PDF]

open access: yes, 2017
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease; the identification of novel targets and development of effective treatment strategies are urgently needed to improve patient outcomes.
Olson, Michael F.   +4 more
core   +1 more source

Transplantation of human immature dental pulp stem cell in dogs with chronic spinal cord injury [PDF]

open access: yesActa Cirúrgica Brasileira, 2017
Purpose: To investigate the therapeutic potential of human immature dental pulp stem cells in the treatment of chronic spinal cord injury in dogs. Methods: Three dogs of different breeds with chronic SCI were presented as animal clinical cases.
Matheus Levi Tajra Feitosa   +8 more
doaj   +1 more source

Two complementary strategies to improve cell engraftment in mesenchymal stem cell-based therapy: Increasing transplanted cell resistance and increasing tissue receptivity

open access: yesCell Adhesion & Migration, 2016
Over the past 2 decades, therapies based on mesenchymal stem cells (MSC) have been tested to treat several types of diseases in clinical studies, due to their potential for tissue repair and regeneration.
F. Ezquer   +3 more
semanticscholar   +1 more source

Regulatory Framework for Advanced Therapy Medicinal Products in Europe and United States

open access: yesFrontiers in Pharmacology, 2019
Advanced therapy medicinal products (ATMPs) are a fast-growing field of innovative therapies. The European Union (EU) and the United States (US) are fostering their development.
Carolina Iglesias-Lopez   +5 more
doaj   +1 more source

Monitoring wound healing of burn in rat model using human Wharton’s jelly mesenchymal stem cells containing cGFP integrated by lentiviral vectors [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2018
Objective(s): Human Wharton’s Jelly mesenchymal stem cells (hWMSCs) are undifferentiated cells commonly used in regenerative medicine. The aim of this study was to develop a reliable tool for tracking hWMSCs when utilized as therapeutics in burnt ...
Mohammad Reza Pourfath   +5 more
doaj   +1 more source

Potential Cell-Based and Cell-Free Therapy for Patients with COVID-19

open access: yesCells, 2022
Since it was first reported, the novel coronavirus disease 2019 (COVID-19) remains an unresolved puzzle for biomedical researchers in different fields. Various treatments, drugs, and interventions were explored as treatments for COVID.
Marselina Irasonia Tan   +7 more
doaj   +1 more source

Effects of rabbit pinna-derived blastema cells on tendon healing [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2020
Objective(s): Tendon healing is substantially slow and often associated with suboptimal repair. Cell therapy is one of the promising methods to improve tendon repair.
Nooshin Ghayemi   +4 more
doaj   +1 more source

Modulation of 5-Aminolevulinic acid mediated photodynamic therapy induced cell death in a human lung adenocarcinoma cell line [PDF]

open access: yes, 2016
Photodynamic therapy (PDT) is a cancer treatment involving the administration of a photosensitising drug which selectively accumulates in tumor tissue, followed by irradiation with appropriate wavelength light.
Battle, A.   +3 more
core   +2 more sources

Mesenchymal Stem Cell-Based Therapy of Inflammatory Lung Diseases: Current Understanding and Future Perspectives

open access: yesStem Cells International, 2019
During acute or chronic lung injury, inappropriate immune response and/or aberrant repair process causes irreversible damage in lung tissue and most usually results in the development of fibrosis followed by decline in lung function.
Randall Harrell   +8 more
semanticscholar   +1 more source

A new era of macrophage-based cell therapy

open access: yesExperimental and Molecular Medicine, 2023
Macrophages are essential innate immune cells found throughout the body that have protective and pathogenic functions in many diseases. When activated, macrophages can mediate the phagocytosis of dangerous cells or materials and participate in effective ...
Y. Na, Sang Wha Kim, S. Seok
semanticscholar   +1 more source

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