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Challenges of Cell Counting in Cell Therapy Products [PDF]

Cell Transplantation
Cell counting is a common and fundamental cell measurement technique that plays a crucial role in the development and quality control of cell therapy products.
Muyun Liu, Wanglong Chu, Tao Guo, Xiuping Zeng, Yan Shangguan, Fangtao He, Xiao Liang   +6 more
doaj   +3 more sources

GenoTox Cell Counter: A mobile App to standardize cell counting in genotoxicity testing [PDF]

Genetics and Molecular Biology
The analysis of genotoxicity assays has long posed a major challenge for the standardization of analyses in environmental and occupational settings, as well as in assessing health impacts across various diseases.
Gumercindo Pimentel-Peralta, Yennifer Alfaro, Juliana Da Silva   +2 more
doaj   +3 more sources

IDCC-SAM: A Zero-Shot Approach for Cell Counting in Immunocytochemistry Dataset Using the Segment Anything Model [PDF]

Bioengineering
Cell counting in immunocytochemistry is vital for biomedical research, supporting the diagnosis and treatment of diseases such as neurological disorders, autoimmune conditions, and cancer. However, traditional counting methods are manual, time-consuming,
Samuel Fanijo, Ali Jannesari, Julie Dickerson   +2 more
doaj   +2 more sources

A Deep Learning-Based Method for Automatic Assessment of Stomatal Index in Wheat Microscopic Images of Leaf Epidermis

Frontiers in Plant Science, 2021
The stomatal index of the leaf is the ratio of the number of stomata to the total number of stomata and epidermal cells. Comparing with the stomatal density, the stomatal index is relatively constant in environmental conditions and the age of the leaf ...
Chuancheng Zhu, Yusong Hu, Hude Mao, Shumin Li, Fangfang Li, Congyuan Zhao, Lin Luo, Weizhen Liu, Weizhen Liu, Xiaohui Yuan, Xiaohui Yuan, Xiaohui Yuan   +11 more
doaj   +1 more source

Deeply-supervised density regression for automatic cell counting in microscopy images. [PDF]

Med Image Anal, 2021
He S, Minn KT, Solnica-Krezel L, Anastasio MA, Li H.   +4 more
europepmc   +2 more sources

A Study on the Uniform Distribution and Counting Method of Raw Cow’s Milk Somatic Cells

Micromachines, 2022
The somatic cell count (SCC) in raw milk is an important basis for determining whether a cow is suffering from mastitis. To address the problem of an uneven distribution of somatic cells due to cell-adherent sedimentation, among other reasons, during ...
Wei Zhou, Xingyu Li, Wanyun Su, Hongbiao Zheng, Guangxin An, Zhilin Li, Shanshan Li   +6 more
doaj   +1 more source

Development of a Single-Piece Sperm Counting Chamber (SSCC) for Aquatic Species

Fishes, 2022
Accurate determination of sperm concentration in aquatic species is important for assisted reproduction and cryopreservation, yet is challenging as current counting methods are costly or not suitable for many species. The goal of this work was to develop
Jorge A. Belgodere, Yue Liu, Elizabeth L. Reich, Jason Eades, Terrence R. Tiersch, William Todd Monroe   +5 more
doaj   +1 more source

Histopathological modeling of status epilepticus-induced brain damage based on in vivo diffusion tensor imaging in rats

Frontiers in Neuroscience, 2022
Non-invasive magnetic resonance imaging (MRI) methods have proved useful in the diagnosis and prognosis of neurodegenerative diseases. However, the interpretation of imaging outcomes in terms of tissue pathology is still challenging.
Isabel San Martín Molina, Raimo A. Salo, Olli Gröhn, Jussi Tohka, Alejandra Sierra   +4 more
doaj   +1 more source

Automatic counting method for complex overlapping erythrocytes based on seed prediction in microscopic imaging [PDF]

Journal of Innovative Optical Health Sciences, 2016
Blood cell counting is an important medical test to help medical staffs diagnose various symptoms and diseases. An automatic segmentation of complex overlapping erythrocytes based on seed prediction in microscopic imaging is proposed.
Xudong Wei, Yiping Cao
doaj   +1 more source

ACDC: Automated Cell Detection and Counting for Time-Lapse Fluorescence Microscopy

Applied Sciences, 2020
Advances in microscopy imaging technologies have enabled the visualization of live-cell dynamic processes using time-lapse microscopy imaging. However, modern methods exhibit several limitations related to the training phases and to time constraints ...
Leonardo Rundo, Andrea Tangherloni, Darren R. Tyson, Riccardo Betta, Carmelo Militello, Simone Spolaor, Marco S. Nobile, Daniela Besozzi, Alexander L. R. Lubbock, Vito Quaranta, Giancarlo Mauri, Carlos F. Lopez, Paolo Cazzaniga   +12 more
doaj   +1 more source