Results 181 to 190 of about 5,958,944 (301)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Open-source cell culture automation system with integrated cell counting for passaging microplate cultures. [PDF]

PNAS Nexus
Courville G, Vaid S, Toruño A, Lebel P, Cabrera JP, Raghavan P, Jacobsen A, Bell GRR, Leonetti MD, Gómez-Sjöberg R.   +9 more
europepmc   +1 more source

Automating cell counting in fluorescent microscopy through deep learning with c-ResUnet. [PDF]

Sci Rep, 2021
Morelli R, Clissa L, Amici R, Cerri M, Hitrec T, Luppi M, Rinaldi L, Squarcio F, Zoccoli A.   +8 more
europepmc   +1 more source

Cell Count [PDF]

, 2020
openaire   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Automated Cell Counting in CSF Diagnostics Revisited-Friend or Foe? [PDF]

Diagnostics (Basel)
Haarmann A, Schubert J, Steigerwald U, Schuhmann MK.   +3 more
europepmc   +1 more source

Validation of an automated cell counting method for cGMP manufacturing of human induced pluripotent stem cells. [PDF]

Biotechnol Rep (Amst), 2022
Manzini P, Peli V, Rivera-Ordaz A, Budelli S, Barilani M, Lazzari L.   +5 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Evaluating the Quality Performance of Sysmex and Mindray Hematology Analyzers for Blood Cell Counting Based on External Quality Assessment Data. [PDF]

Int J Lab Hematol
He D, Zhou C, Long Z, Liu Y, Wu X, Wang L, Zhang Y, Kong L.   +7 more
europepmc   +1 more source

Machine learning-based automated fungal cell counting under a complicated background with ilastik and ImageJ. [PDF]

Eng Life Sci, 2021
Li C, Ma X, Deng J, Li J, Liu Y, Zhu X, Liu J, Zhang P.   +7 more
europepmc   +1 more source