Results 241 to 250 of about 5,958,944 (301)
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
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Current Protocols in Cytometry, 1997
AbstractThis unit presents protocols for counting cells using either a hemacytometer or electronically using a Coulter counter. Cell counting with a hemacytometer permits effective discrimination of live from dead cells using trypan blue exclusion. In addition, the procedure is less subject to errors arising from cell clumping or size heterogeneity ...
M C, Phelan, G, Lawler
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AbstractThis unit presents protocols for counting cells using either a hemacytometer or electronically using a Coulter counter. Cell counting with a hemacytometer permits effective discrimination of live from dead cells using trypan blue exclusion. In addition, the procedure is less subject to errors arising from cell clumping or size heterogeneity ...
M C, Phelan, G, Lawler
openaire +2 more sources
Platelet Count Is Positively Correlated with White Cell Count and Red Cell Count
Haemostasis, 2009Platelet count is positively correlated with the white cell count in healthy males aged 20–68 years (p < 0.002) and in healthy medical students of both sexes aged 18–22 years (p < 0.0001). Platelet count is also positively correlated with red cell count in healthy males (p < 0.02).
P C, Milner, S, Johl, J F, Martin
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White Blood Cell Count and Differential Count
Emergency Medicine Clinics of North America, 1986Current methods for performing the white blood cell count and differential count along with recent technologic advances are discussed. Sources of error and variation in these tests are presented. The use of the white blood cell count and the differential count in a variety clinical situations is reviewed.
H A, Werman, C G, Brown
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Archives of Internal Medicine, 1959
Addis1,2established the fact 30 years ago, with use of a counting chamber, that both white and red cells normally occur in urine. He found top values of 2,000,000 white cells and 400,000 red cells in the 12-hour night urine specimens of 74 apparently healthy medical students.
openaire +2 more sources
Addis1,2established the fact 30 years ago, with use of a counting chamber, that both white and red cells normally occur in urine. He found top values of 2,000,000 white cells and 400,000 red cells in the 12-hour night urine specimens of 74 apparently healthy medical students.
openaire +2 more sources
Counting stem cells: methodological constraints
Nature Methods, 2012The number of stem cells contributing to hematopoiesis has been a matter of debate. Many studies use retroviral tagging of stem cells to measure clonal contribution. Here we argue that methodological factors can impact such clonal analyses. Whereas early studies had low resolution, leading to underestimation, recent methods may result in an ...
Bystrykh, Leonid V +4 more
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Pediatrics, 1986
I read with interest the article by Portnoy and Olson on normal cerebrospinal fluid cell (CSF) counts. However, I believe there are a number of problems in accepting that the information presented lives up to the title. First, they fail to state what their criteria were for confidently excluding central nervous system (CNS) infection.
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I read with interest the article by Portnoy and Olson on normal cerebrospinal fluid cell (CSF) counts. However, I believe there are a number of problems in accepting that the information presented lives up to the title. First, they fail to state what their criteria were for confidently excluding central nervous system (CNS) infection.
openaire +2 more sources