Results 141 to 150 of about 10,542,794 (310)
Cell culture engineering: part 1 [Frontiers of biomedical engineering]
, 2014 Educação Superior::Ciências Biológicas::BioquímicaEducação Superior::Engenharias::Engenharia BiomédicaEducação Superior::Ciências Biológicas::Biologia GeralEducação Superior::Ciências Biológicas::GenéticaPresents a lecture by Professor Saltzman.
Saltzman, W. Mark
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Development of a novel high-throughput culture system for hypoxic 3D hydrogel cell culture
Scientific ReportsAnimal models lack physiologic relevance to the human system which results in low clinical translation of results derived from animal testing. Besides spheroids or organoids, hydrogel-based 3D in vitro models are used to mimic the in vivo situation ...
Dominik Egger +5 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor-Microenvironment-on-Chip Platform for Assessing Drug Response in 3D Dynamic Culture
Microphysiological systems involving microfluidic 3D culture of cancer cells have emerged as a versatile toolkit to study tumor biological problems and evaluate potential treatment strategies.
Acar, Ahmet +4 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Monitoring Tools for the Development of High Cell Density Culture Strategies
Biopharmaceuticals market has been constantly increasing during the last years, what is transforming the manufacturing industry of biomolecules. The efforts have been put into better understanding how bioprocesses are regulated in order to firstly, build
Comas Sánchez, Pere +3 more
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
This volume introduces a new concept that boldly breaks through the traditional dichotomy of high and low culture while offering a fresh approach to both: unpopular culture.
core +1 more source
Culture and utilization of freshwater algae as protein source [PDF]
, 1990 A discussion is presented on the commercial production of algae in mass culture conditions as a source of single-cell protein. Particular reference is made to the food situation in the Philippines, and research conducted by the Institute of Science and ...
Rodulfo, Bienvenida R.
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