Results 151 to 160 of about 17,196,917 (410)

Clinical Presentation and Diagnosis of Smith-Lemli-Opitz Syndrome: First Case Report from Sudan

Sudan Journal of Medical Sciences
Background: Smith-Lemli-Opitz syndrome (SLOS) is a congenital autosomal recessive disorder characterized by defective cholesterol metabolism, attributable to a deficiency of the enzyme 7-dehydrocholesterol reductase (DHCR7) caused by mutations in the ...
Rayan Khalid, Dalia Omer, Tarig Alsheikh, Imad Fadl-Elmula   +3 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Culture adaptation of embryonic stem cells echoes germ cell malignancy [PDF]

, 2007
Neil J. Harrison, Duncan Baker, Peter W. Andrews   +2 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Stochastic Model of Autocrine and Paracrine Signals in Cell Culture Assays [PDF]

, 2003
Lazaros Batsilas, Alexander M. Berezhkovskii, Stanislav Y. Shvartsman   +2 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

In vitro detection of pathogenic Listeria monocytogenes from food sources by conventional, molecular and cell culture method [PDF]

, 2013
Javed Ahamad Khan, R. Rathore, Sarah Ahmad Khan, Iqbal Ahmad   +3 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Assessing morpho-chemical and genetic diversity in acid limes germplasm using microsatellite markers

Notulae Botanicae Horti Agrobotanici Cluj-Napoca
Acid limes are highly nutraceutical and have great market demand. In Pakistan, two lime varieties are cultivated including ‘Mexican lime’ and ‘Eustis limequat’. Hence, other potential varieties were characterized for morphogenetic variability.
Arooge FATIMA, Muhammad USMAN, Bilquees FATIMA, Iqrar Ahmad RANA   +3 more
doaj   +1 more source

History of Cell Culture

, 2017
From the ancient Romans, through the Middle Ages, to the late of the nineteenth cen‐ tury, the Aristotelian doctrine of spontaneous generation was one of the most basic laws. Even the invention of the microscope and investigations of Leeuwenhoek and Hook
Magdalena Jędrzejczak-Silicka
semanticscholar   +1 more source