Results 151 to 160 of about 2,061,986 (268)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Porcine Single-Eye Retinal Pigment Epithelium Cell Culture for Barrier and Polarity Studies. [PDF]
Dörschmann P+4 more
europepmc +1 more source
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
Food culture and cell-culture: technical, ethical and social frontiers. [PDF]
Chriki S+4 more
europepmc +1 more source
Culture of Human Leukaemic Blood Cells In Vitro. Normal and Abnormal Cell Division and Maturation
F. W. Gunz
openalex +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
Interferon-induced immune signatures are associated with suppression of HEV infection in porcine cell culture models. [PDF]
Schlienkamp S+11 more
europepmc +1 more source
Alkaline Phosphatase Content and the Effects of Prednisolone on Mammalian Cells in Culture [PDF]
Rody P. Cox, Colin M. MacLeod
openalex +1 more source