Advanced microfluidic and 3D cell culture platforms for modeling vascularization in diabetic foot ulcers: A systematic review of translational challenges and perspectives. [PDF]
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Abstract Gas exchange, introduction of nutrients, and removal of waste products can be regulated in a new device for continuous sustained culture of cells in suspension. Strain L, clone 929, fibroblasts; HeLa cells; and strains KB, and Chang, liver cells were successfully propagated in this device.
S, GRAFF, K S, McCARTY
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Microfluidic techniques allow precise control of fluids and particles at the nanoliter scale and facilitate simultaneous manipulation and analysis of cultured cells, starting from a single cell to larger populations and to intact tissues. The use of integrated microfluidic devices has considerably advanced the fields of quantitative and systems biology.
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