Results 241 to 250 of about 17,196,917 (410)

Protocol for Establishing a Multiplex Image-based Autophagy RNAi Screen in Cell Cultures

, 2017
Jennifer Jung, Christian Behrends
openalex   +1 more source

Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?

British Journal of Pharmacology, 2004
B. Halliwell, M. Whiteman
semanticscholar   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Exploring the Multifaceted Neuroprotective Mechanisms of Bovine Lactoferrin in a Cell Culture Model of Parkinson's Disease. [PDF]

Int J Mol Sci
Ianiro G, Martella N, Niro A, Colardo M, Valenti P, Musci G, Cutone A, Segatto M.   +7 more
europepmc   +1 more source

Quantitative Analyses of Synergistic Responses between Cannabidiol and DNA-Damaging Agents on the Proliferation and Viability of Glioblastoma and Neural Progenitor Cells in Culture [PDF]

, 2016
Liting Deng, Lindsay Ng, Tatsuya Ozawa, Nephi Stella   +3 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Open-source cell culture automation system with integrated cell counting for passaging microplate cultures. [PDF]

PNAS Nexus
Courville G, Vaid S, Toruño A, Lebel P, Cabrera JP, Raghavan P, Jacobsen A, Bell GRR, Leonetti MD, Gómez-Sjöberg R.   +9 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Bridging the gap in Parkinson's disease research: from general pathophysiology to advanced 3d cell culture models. [PDF]

Cell Commun Signal
Keles B, Rumman B, Samarie MAJA, Gürsoy Özdemir Y, Öztop Cakmak Ö, Akyoldas G, Ertan S, Sokullu E.   +7 more
europepmc   +1 more source

Cathepsin X-deficient Gastric Epithelial Cells in Co-culture with Macrophages [PDF]

, 2010
Anja Bernhardt, Doerthe Kuester, Albert Roessner, Thomas Reinheckel, Sabine Krueger   +4 more
openalex   +1 more source