Results 251 to 260 of about 17,196,917 (410)

Three‐dimensional cell culture models for anticancer drug screening: Worth the effort?

Journal of Cellular Physiology, 2018
E. Verjans, Jordi Doijen, W. Luyten, B. Landuyt, L. Schoofs   +4 more
semanticscholar   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Opposite effects of spermidine and GC7 in cell culture are dictated by distinct molecular targets. [PDF]

Biochem J
Tahara T, Bordone R, Campese AF, Cantale Aeo NM, Astolfi R, Coni S, Ragno R, Canettieri G, Agostinelli E.   +8 more
europepmc   +1 more source

COMPARATIVE STUDY OF NATURE OF MEASLES VIRUS AND DISTEMPER VIRUS IN DOG KIDNEY CELL CULTURES

, 1967
Jutarō Tawara
openalex   +2 more sources

Hydrogels as extracellular matrix mimics for 3D cell culture.

Biotechnology and Bioengineering, 2009
M. Tibbitt, K. Anseth
semanticscholar   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Label-free in-line characterization of immune cell culture using quantitative phase imaging. [PDF]

NPJ Regen Med
Serafini CE, Gorti V, Casteleiro Costa P, Silva Trenkle AD, Kanwar B, Wang B, Wicker B, Kippner LE, LeCompte I, Chen RQ, Joffe B, Li Y, Bowles-Welch AC, Li J, Brown CE, Kwong GA, Balakirsky S, Roy K, Robles FE.   +18 more
europepmc   +1 more source

A METABOLIC MODEL FOR THE MEGALOBLASTIC ANEMIA USING IN VITRO L1210 CELL CULTURE SYSTEM

, 1989
H Yatabe, Hiromasa Yamauchi, Masamitsu Karasawa, Mitsuhiro Omine, Tadashi Maekawa   +4 more
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Scale-Up Strategy Focused on Hydrodynamic Stress for Mammalian Cell Culture Established by a Dry-Wet Approach. [PDF]

Eng Life Sci
Kenmoku H, Kaneko A, Saito T, Nemoto T, Kato Y, Ohira S.   +5 more
europepmc   +1 more source