Results 281 to 290 of about 17,041,985 (363)

Expansion and characteristics of human T regulatory type 1 cells in co-cultures simulating tumor microenvironment

, 2007
Christoph Bergmann, Laura Strauss, Reinhard Zeidler, Stephan Lang, Theresa L. Whiteside   +4 more
openalex   +2 more sources

Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices.

Biosensors & bioelectronics, 2015
S. Halldorsson, E. Lucumi, Rafael Gómez-Sjöberg, R. Fleming   +3 more
semanticscholar   +1 more source

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

From monolayer to spheroid: assessing influenza a virus infection in 2D and 3D cell culture of A549 and HEK293. [PDF]

Virol J
Shokouhi H, Gholizadeh F, Sokhandan H, Sisakht MM, Mehrbod P.   +4 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Promoting ethical and reproducible cell culture: implementing animal-free alternatives to teaching in molecular and cell biology. [PDF]

Front Toxicol
Nessar A, Röhrs V, Ziersch M, Ali ASM, Moradi J, Kurreck A, Berg J, Kurreck J.   +7 more
europepmc   +1 more source

21st Century Cell Culture for 21st Century Toxicology.

Chemical Research in Toxicology, 2017
D. Pamies, T. Hartung
semanticscholar   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Quantitative phase imaging for cell culture quality control

Cytometry Part A, 2017
L. Kastl, Michael Isbach, D. Dirksen, J. Schnekenburger, B. Kemper   +4 more
semanticscholar   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source