TMC4 localizes to multiple taste cell types in the mouse taste papillae
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Red and near-infrared light treatment can change the intensity of biophoton emissions in cell culture. [PDF]
Hoh Kam J +4 more
europepmc +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Injectable Nanocomposite Biomaterial for 3D Printing of Personalized Matrices and Their Use in Bioreactors for Bioengineering Advanced Cell Culture Models. [PDF]
Campodoni E +8 more
europepmc +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Thionine modulates tau phosphorylation in an Alzheimer's disease cell culture model. [PDF]
Önder S, Biberoğlu K, Tacal Ö.
europepmc +1 more source
Correction to "Size Distribution Measurement of Insoluble Particles in PM2.5 Dispersed in Cell Culture Medium Using Aerosolization Techniques". [PDF]
Kuruma Y, Sakurai H, Okuda T.
europepmc +1 more source
Viniferin-Rich Phytocomplex from <i>Vitis vinifera</i> L. Plant Cell Culture Mitigates Neuroinflammation in BV2 Microglia Cells. [PDF]
Videtta G +10 more
europepmc +1 more source

