Blockade of electrical activity promotes the death of mammalian retinal ganglion cells in culture.
Stuart A. Lipton
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Circular RNAs modulate cell death in cardiovascular diseases. [PDF]
Pan R, Koo C, Su W, You Q, Guo H, Liu B.
europepmc +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme. [PDF]
Sharad Kumar+4 more
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The role of programmed cell death in renal cancer: a bibliometric perspective (1998-2024). [PDF]
Hong L, Zhao C, Wu T, Hu X, Li X, Li L.
europepmc +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos. [PDF]
W S Chen+7 more
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Cell death signaling in human erythron: erythrocytes lose the complexity of cell death machinery upon maturation. [PDF]
Tkachenko A, Havranek O.
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In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source