Results 241 to 250 of about 3,407,912 (356)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

AIM2 drives inflammatory cell death and monkeypox pathogenesis. [PDF]

Cell Mol Immunol
Oh J, Hwang YH, Lee J, Seok C, Oh S, Kim HY, Mariam N, Ahn J, Yu G, Park J, Kim H, Kim S, Shin S, Jung MC, Gil J, Lee JS, Choi YK, Kim D, Kim D, Kim YJ, Lee S.   +20 more
europepmc   +1 more source

Lycopene protects human SH-SY5Y neuroblastoma cells against hydrogen peroxide-induced death via inhibition of oxidative stress and mitochondria-associated apoptotic pathways

, 2016
Chunsheng Feng, Tianfei Luo, Shuyan Zhang, Kai Liu, Yanhong Zhang, Yinan Luo, Pengfei Ge   +6 more
openalex   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Yeast NatB Regulates Cell Death of Bax-Expressing Cells. [PDF]

Biomolecules
Guedes JP, Mendes F, Machado BO, Manon S, Côrte-Real M, Chaves SR.   +5 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Editorial: Cell death mechanisms in neurodegenerative disorders. [PDF]

Front Cell Dev Biol
Tare M, D'Orsi B, Singh A.
europepmc   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

BMP-Dependent Modulation of ROS Generation and Scavenging Controls Interdigital Cell Death. [PDF]

Dev Growth Differ
Ono SF, Furukawa R, Cordeiro IR, Kabashima K, Yoshida K, Hatano T, Hayafune K, Kashima M, Kagehira A, Yu R, Kawanishi T, Tanaka M.   +11 more
europepmc   +1 more source

Machine learning-based biomarker screening for acute myeloid leukemia prognosis and therapy from diverse cell-death patterns [PDF]

Yu Qin, Xuexue Pu, Dingtao Hu, Mingzhen Yang   +3 more
openalex   +1 more source