Results 341 to 350 of about 3,157,910 (364)
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Death and the cell

Immunology Today, 1986
Cell death is an important component of many - perhaps all - immunological reactions. Target cells die after attack by complement, cytotoxic T lymphocytes, K cells, NK cells or lymphotoxins. In lymphoid cells themselves death occurs in parallel with proliferation in the normal thymus and in the periphery during immune responses.
Andrew H. Wyllie, E Duvall
openaire   +3 more sources

CELL INJURY AND CELL DEATH [PDF]

open access: possible, 2011
WHEN CELLS are damaged, as often occurs during trauma and metabolic stress, the organism has to choose whether to repair the damage by promoting cell survival or remove irreparably injured cells. Cell injury occurs when an adverse stimulus reversibly disrupts the normal, complex homeostatic balance of the cellular metabolism. In this case, after injury
BARONI, Adone   +3 more
openaire   +5 more sources

DNA and cell death

Cytotechnology, 1991
The type of DNA damage and the role of poly (ADP-ribosyl) polymerase (ADPRP) and sulphated glyprotein 2 (SGP-2) in programmed cell death (apoptosis) was investigated in the following model systems: i) rat thymocytes treated with dexamethasone (DEX) eitherin vitro orin vivo; ii) human perypheral blood mononuclear cells (hPBMCs) exposed to oxygen free ...
MONTI, DANIELA   +8 more
openaire   +4 more sources

Mechanisms of cell death

Archives of Toxicology, 1989
Two distinct morphological patterns of cell death have been recognized, termed necrosis and apoptosis. Apoptosis, or programmed cell death, occurs in both physiological and pathological conditions. It arises due to an elevation of cytosolic free calcium concentration resulting in activation of a nuclear endonuclease.
Donald S. Davies   +2 more
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Programmed Cell Death

Science, 1996
Letters from: [ Jan Novak ][1] [ Alice B. Fulton ][1] [ Jean Claude Ameisen ][1] Jean Claude Ameisen's Perspective “The origin of programmed cell death [PCD]” ([31 May, p. 1278][2]) discusses possible evolutionary roots of cell suicide.
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Phosphatidylcholine and cell death

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002
Phosphatidylcholine (PC) constitutes a major portion of cellular phospholipids and displays unique molecular species in different cell types and tissues. Inhibition of the CDP-choline pathway in most mammalian cells or overexpression of the hepatic phosphatidylethanolamine methylation pathway in hepatocytes leads to perturbation of PC homeostasis ...
Zheng Cui, Martin Houweling
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Neurotrophins and cell death

Experimental Cell Research, 2012
The neurotrophins - NGF, BDNF, NT-3 - are secreted proteins that play a major role in neuron survival, differentiation and axon wiring toward target territories. They do so by interacting with their main tyrosine kinase receptors TrkA, TrkB, TrkC and p75(NTR). Even though there is a general consensus on the view that neurotrophins are survival factors,
Ichim, Gabriel   +2 more
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Calcium and Cell Death

2007
Calcium signalling system controls majority of cellular reactions. Calcium signals occurring within tightly regulated temporal and spatial domains, govern a host of Ca2(+)-dependent enzymes, which in turn determine specified cellular responses. Generation of Ca2+ signals is achieved through coordinated activity of several families of Ca2+ channels and ...
Verkhratsky, Alexej   +1 more
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Targeting Cell Death

Clinical Pharmacology & Therapeutics, 2007
Functional consequences of myocardial or cerebral infarction are the result of excessive cell death. It is patent that preventing cell death is the therapeutic goal in any ischemia-reperfusion setting. Mitochondria amplify apoptotic cascades and have emerged as crucial organelles in ischemia-reperfusion.
Hausenloy DJ, SCORRANO, LUCA
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