Results 301 to 310 of about 2,690,374 (356)
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Extrathymic T cell differentiation
Current Opinion in Immunology, 1995In the mouse, the gut mucosa is a major site of extrathymic differentiation of T cells. Recent data in this past year show that this process differs from the main thymic differentiation pathway not only in its location, but also in its use of costimulatory molecules, signal transduction modules, and mechanisms of repertoire selection. The thymus exerts
B, Rocha, D, Guy-Grand, P, Vassalli
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1995
B-cell develop their B-cell receptor (BCR) via transient formation of surrogate L-chain/p55 complexes.
H.-Harald Sedlacek, Tarik Möröy
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B-cell develop their B-cell receptor (BCR) via transient formation of surrogate L-chain/p55 complexes.
H.-Harald Sedlacek, Tarik Möröy
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Cell Differentiation and Malignancy
Cell Biophysics, 1986An understanding of the mechanism that controls growth and differentiation in normal cells would seem to be an essential requirement to elucidate the origin and reversibility of malignancy. For this approach I have mainly used normal and leukemic blood cells, and in most studies have used myeloid blood cells as a model system.
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Science's STKE, 2006
This 3-week-long series of collaborative laboratory exercises explores how to use a cultured cell system (PC12 cells) to study signaling pathways involved in cellular differentiation. The laboratory would be useful in a neurobiology or cell biology course for advanced undergraduate students.
Elizabeth M, Adler +2 more
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This 3-week-long series of collaborative laboratory exercises explores how to use a cultured cell system (PC12 cells) to study signaling pathways involved in cellular differentiation. The laboratory would be useful in a neurobiology or cell biology course for advanced undergraduate students.
Elizabeth M, Adler +2 more
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1987
All lymphocytes are derived from an unidentified multipotent precursor (Fig. 10.1). T cell precursors migrate from the liver and bone marrow in fetal life and from the bone marrow in adult life, to the thymus. It is unknown whether the stem cells become committed to T cell differentiation before or after they have entered the thymus.
Ian J. Forbes, Anthony S-Y. Leong
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All lymphocytes are derived from an unidentified multipotent precursor (Fig. 10.1). T cell precursors migrate from the liver and bone marrow in fetal life and from the bone marrow in adult life, to the thymus. It is unknown whether the stem cells become committed to T cell differentiation before or after they have entered the thymus.
Ian J. Forbes, Anthony S-Y. Leong
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Glycolipids and Cell Differentiation
1980Differentiation of a cultured cell refers generally to a change in the expression of some peculiar functions specific to this cell. Generally differentiation involves only a modification of some biochemical properties of the cell such as synthesis of melanin by melanocytes (KREIDER et al., 1975) or synthesis of collagen by bone fibroblasts (MANNER and ...
G, Rebel, J, Robert, P, Mandel
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Erythroid cell differentiation
Molecular and Cellular Biochemistry, 1978Normal and transformed erythroid cell precursors provide the opportunity for study of a number of problems relevant to the regulation of proliferation and differentiation in a developmental system. Evidence is presented which suggests that the hormone, erythropoietin, has a primary role in regulating precursor cell proliferation.
M, Terada, P A, Marks, R A, Rifkind
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Synchronous Cell Differentiation
1968Publisher Summary Synchronous cell differentiation refers to the occurrence of simultaneous cellular transformations throughout a population of cells. Although the induction of cell division synchrony may be a prerequisite for such an experimental situation, it need not be the primary concern of the investigator.
G M, Padilla, I L, Cameron
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Differentiation of Human T Cells
Clinics in Laboratory Medicine, 1988This article discusses the ontogeny of human T cells along with the relationship of normal T-cell maturation to the development of various malignant T-cell syndromes. The impact of monoclonal antibody technology, the discovery of the T-cell receptor for antigen, and the discovery of mechanisms of thymocyte-thymic microenvironment interactions on the ...
S M, Denning, B F, Haynes
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Current Opinion in Cell Biology, 1989
The appeal of myogenic differentiation as a model developmental system derives in part from the complexity of regulatory steps required to account for the diversity of muscle structure and function. The intricate patterns of contractile tissue formation in the adult animal depend on the orderly progression of molecular signals that lead primordial ...
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The appeal of myogenic differentiation as a model developmental system derives in part from the complexity of regulatory steps required to account for the diversity of muscle structure and function. The intricate patterns of contractile tissue formation in the adult animal depend on the orderly progression of molecular signals that lead primordial ...
openaire +2 more sources