Results 171 to 180 of about 12,032,873 (351)

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Supplementary Figure 3 from Identifying and Targeting <i>ROS1</i> Gene Fusions in Non–Small Cell Lung Cancer

, 2023
Kurtis D. Davies, Anh‐Tuan Le, Mariana F. Theodoro, Margaret C. Skokan, Dara L. Aisner, Eamon M. Berge, Luigi Terracciano, Federico Cappuzzo, Matteo Incarbone, Massimo Roncalli, Marco Alloisio, Armando Santoro, D. Ross Camidge, Marileila Varella-Garcia, Robert C. Doebele   +14 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Moesin controls cell-cell fusion and osteoclast function. [PDF]

J Cell Biol
Dufrançais O, Plozza M, Juzans M, Métais A, Monard SC, Bordignon PJ, Verdys P, Sanchez T, Bergert M, Halper J, Panebianco CJ, Mascarau R, Gence R, Arnaud G, Ben Neji M, Maridonneau-Parini I, Le Cabec V, Boerckel JD, Pavlos NJ, Diz-Muñoz A, Lagarrigue F, Blin-Wakkach C, Carréno S, Poincloux R, Burkhardt JK, Raynaud-Messina B, Vérollet C.   +26 more
europepmc   +1 more source

Impaired potency of neutralizing antibodies against cell-cell fusion mediated by SARS-CoV-2. [PDF]

Emerg Microbes Infect, 2023
Wang Q, Yeh AY, Guo Y, Mohri H, Yu J, Ho DD, Liu L.   +6 more
europepmc   +1 more source

Supplementary Table S3 from Mutational Analysis of Gene Fusions Predicts Novel MHC Class I–Restricted T-Cell Epitopes and Immune Signatures in a Subset of Prostate Cancer

, 2023
Jennifer L. Kalina, David S. Neilson, Yen‐Yi Lin, Phineas T. Hamilton, Alexandra P. Comber, Emma M.H. Loy, S. Cenk Sahinalp, Colin C. Collins, Faraz Hach, Julian J. Lum   +9 more
openalex   +1 more source

Knockdown of hspg2 is associated with mandibular jaw joint fusion and neural crest cell dysfunction in zebrafish [PDF]

, 2020
Barbara S. Castellanos, Anita M. Quintana   +1 more
openalex   +1 more source

Molecular Mechanisms Regulating Cell Fusion and Heterokaryon Formation in Filamentous Fungi

Microbiology spectrum, 2017
Asen Daskalov, Jens Heller, S. Herzog, A. Fleissner, N. L. Glass, Joseph Heitman, Neil A. R. Gow   +6 more
semanticscholar   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Pannexin 1 induces Rhabdomyosarcoma cell fusion by downregulating APOBEC2. [PDF]

Oncogenesis
Welten A, Bera A, Langlois S, Xiang X, Gupta K, Freeman E, Cowan KN.   +6 more
europepmc   +1 more source