Results 11 to 20 of about 12,374,157 (394)

Virus-Mediated Cell-Cell Fusion [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Cell-cell fusion between eukaryotic cells is a general process involved in many physiological and pathological conditions, including infections by bacteria, parasites, and viruses.
Héloïse Leroy   +6 more
semanticscholar   +5 more sources

Regulation of cell-cell fusion by nanotopography [PDF]

open access: yesScientific Reports, 2016
Cell-cell fusion is fundamental to a multitude of biological processes ranging from cell differentiation and embryogenesis to cancer metastasis and biomaterial-tissue interactions. Fusogenic cells are exposed to biochemical and biophysical factors, which
Jagannath Padmanabhan   +11 more
semanticscholar   +4 more sources

Distinct Requirements for HIV-Cell Fusion and HIV-mediated Cell-Cell Fusion* [PDF]

open access: yesJournal of Biological Chemistry, 2015
Background: Determinants of HIV-1 fusion with the plasma membrane versus endosomal membrane are unknown. Results: Unlike HIV-cell fusion, HIV-mediated fusion of the plasma membranes of adjacent cells occurred with much lower probability and was actin ...
N. Kondo   +4 more
semanticscholar   +4 more sources

The hallmarks of cell-cell fusion [PDF]

open access: yesDevelopment, 2017
Cell-cell fusion is essential for fertilization and organ development. Dedicated proteins known as fusogens are responsible for mediating membrane fusion. However, until recently, these proteins either remained unidentified or were poorly understood at the mechanistic level. Here, we review how fusogens surmount multiple energy barriers to mediate cell-
Javier M Hernández, B. Podbilewicz
semanticscholar   +4 more sources

Confusion on Cell Fusion [PDF]

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2021
Cell fusion, whereby two cells merge to create one, has been widely described in development, but the role of cell fusion in tissue regeneration and homeostasis remains an open debate. We propose that the regenerative capacity of the gut can be fully attributed to extensive plasticity of the intestinal epithelium.
Louis Vermeulen, Rana Ramadan
openaire   +4 more sources

Flagging fusion: Phosphatidylserine signaling in cell–cell fusion [PDF]

open access: yesJournal of Biological Chemistry, 2021
Formations of myofibers, osteoclasts, syncytiotrophoblasts, and fertilized zygotes share a common step, cell-cell fusion. Recent years have brought about considerable progress in identifying some of the proteins involved in these and other cell-fusion processes.
Jarred M. Whitlock   +1 more
openaire   +3 more sources

Preparation of Monoclonal Antibody against Deoxynivalenol and Development of Immunoassays

open access: yesToxins, 2022
Fusarium toxins are the largest group of mycotoxins, which contain more than 140 known secondary metabolites of fungi. Deoxynivalenol (DON) is one of the most important compounds of this class due to its high toxicity and its potential to harm mankind ...
Hoyda Elsir Mokhtar   +4 more
doaj   +1 more source

The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner

open access: yesViruses, 2020
Although infection by SARS-CoV-2, the causative agent of coronavirus pneumonia disease (COVID-19), is spreading rapidly worldwide, no drug has been shown to be sufficiently effective for treating COVID-19. We previously found that nafamostat mesylate, an
Mizuki Yamamoto   +13 more
semanticscholar   +1 more source

Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly. [PDF]

open access: yes, 2015
Nipah virus (NiV) is a paramyxovirus that infects host cells through the coordinated efforts of two envelope glycoproteins. The G glycoprotein attaches to cell receptors, triggering the fusion (F) glycoprotein to execute membrane fusion.
Aguilar, Hector C   +14 more
core   +7 more sources

Reciprocal t(9;22) ABL/BCR fusion proteins: leukemogenic potential and effects on B cell commitment [PDF]

open access: yes, 2009
Background: t(9;22) is a balanced translocation, and the chromosome 22 breakpoints (Philadelphia chromosome – Ph+) determine formation of different fusion genes that are associated with either Ph+ acute lymphatic leukemia (Ph+ ALL) or chronic myeloid ...
Henschler, Reinhard   +4 more
core   +21 more sources

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