Results 11 to 20 of about 12,032,873 (351)
Definitions, 2020 A technique to form a single hybrid cell, by fusion of two or more dissimilar cells, either spontaneously or by induced fusion. The cells fuse and coalesce, but their nuclei may remain separated.
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Virus-Mediated Cell-Cell Fusion [PDF]
International Journal of Molecular Sciences, 2020 Cell-cell fusion between eukaryotic cells is a general process involved in many physiological and pathological conditions, including infections by bacteria, parasites, and viruses.
Héloïse Leroy +6 more
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Distinct Requirements for HIV-Cell Fusion and HIV-mediated Cell-Cell Fusion* [PDF]
Journal of Biological Chemistry, 2015 Background: Determinants of HIV-1 fusion with the plasma membrane versus endosomal membrane are unknown. Results: Unlike HIV-cell fusion, HIV-mediated fusion of the plasma membranes of adjacent cells occurred with much lower probability and was actin ...
N. Kondo +4 more
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The hallmarks of cell-cell fusion [PDF]
Development, 2017 Cell-cell fusion is essential for fertilization and organ development. Dedicated proteins known as fusogens are responsible for mediating membrane fusion. However, until recently, these proteins either remained unidentified or were poorly understood at the mechanistic level. Here, we review how fusogens surmount multiple energy barriers to mediate cell-
Javier M Hernández, B. Podbilewicz
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Flagging fusion: Phosphatidylserine signaling in cell–cell fusion [PDF]
Journal of Biological Chemistry, 2021 Formations of myofibers, osteoclasts, syncytiotrophoblasts, and fertilized zygotes share a common step, cell-cell fusion. Recent years have brought about considerable progress in identifying some of the proteins involved in these and other cell-fusion processes.
Jarred M. Whitlock +1 more
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Confusion on Cell Fusion [PDF]
Cellular and Molecular Gastroenterology and Hepatology, 2021 Cell fusion, whereby two cells merge to create one, has been widely described in development, but the role of cell fusion in tissue regeneration and homeostasis remains an open debate. We propose that the regenerative capacity of the gut can be fully attributed to extensive plasticity of the intestinal epithelium.
Ramadan, Rana, Vermeulen, Louis
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Viruses, 2023 Human endogenous retrovirus type W (HERV-W) is expressed in various cancers. We previously developed an adenovirus-vectored cancer vaccine targeting HERV-W by encoding an assembled HERV-W group-specific antigen sequence and the HERV-W envelope sequence ...
Isabella Skandorff +7 more
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Generating Heterokaryotic Cells via Bacterial Cell-Cell Fusion
Microbiology Spectrum, 2022 Fusion of cells is an important and common biological process that leads to the mixing of cellular contents and the formation of multinuclear cells. Cell fusion occurs when distinct membranes are brought into proximity of one another and merge to become ...
Shraddha Shitut +7 more
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Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion
bioRxiv, 2020 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects cells by binding to the host cell receptor Ace2 and undergoing virus-host membrane fusion.
G. Papa +11 more
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Cells, 2022 Cre/loxP recombination is a well-established technique increasingly used for modifying DNA both in vitro and in vivo. Nucleotide alterations can be edited in the genomes of mammalian cells, and genetic switches can be designed to target the expression or
Hsiang-Ching Tseng +3 more
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