Results 11 to 20 of about 1,323,463 (353)
Confusion on Cell Fusion [PDF]
Cellular and Molecular Gastroenterology and Hepatology, 2021 Cell fusion, whereby two cells merge to create one, has been widely described in development, but the role of cell fusion in tissue regeneration and homeostasis remains an open debate. We propose that the regenerative capacity of the gut can be fully attributed to extensive plasticity of the intestinal epithelium.
Louis Vermeulen, Rana Ramadan
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Flagging fusion: Phosphatidylserine signaling in cell–cell fusion [PDF]
Journal of Biological Chemistry, 2021 Formations of myofibers, osteoclasts, syncytiotrophoblasts, and fertilized zygotes share a common step, cell-cell fusion. Recent years have brought about considerable progress in identifying some of the proteins involved in these and other cell-fusion processes.
Jarred M. Whitlock +1 more
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Virus-Mediated Cell-Cell Fusion [PDF]
International Journal of Molecular Sciences, 2020 Cell-cell fusion between eukaryotic cells is a general process involved in many physiological and pathological conditions, including infections by bacteria, parasites, and viruses. As obligate intracellular pathogens, viruses use intracellular machineries and pathways for efficient replication in their host target cells. Interestingly, certain viruses,
Lucie Bracq +14 more
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The hallmarks of cell-cell fusion [PDF]
Development, 2017 Cell-cell fusion is essential for fertilization and organ development. Dedicated proteins known as fusogens are responsible for mediating membrane fusion. However, until recently, these proteins either remained unidentified or were poorly understood at the mechanistic level. Here, we review how fusogens surmount multiple energy barriers to mediate cell-
Javier M. Hernández +1 more
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Histochemistry and Cell Biology, 2008 Cell fusions are important to fertilization, placentation, development of skeletal muscle and bone, calcium homeostasis and the immune defense system. Additionally, cell fusions participate in tissue repair and may be important to cancer development and progression.
Larsson, Lars-Inge +2 more
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Regulation of cell-cell fusion by nanotopography [PDF]
Scientific Reports, 2016 AbstractCell-cell fusion is fundamental to a multitude of biological processes ranging from cell differentiation and embryogenesis to cancer metastasis and biomaterial-tissue interactions. Fusogenic cells are exposed to biochemical and biophysical factors, which could potentially alter cell behavior.
Emily R. Kinser +12 more
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TAGLN2-Regulated Trophoblast Migration, Invasion and Fusion are Impaired in Preeclampsia
Frontiers in Cell and Developmental Biology, 2022 Preeclampsia (PE) is a serious disease during pregnancy that affects approximately eight million mothers and infants worldwide each year and is closely related to abnormal trophoblast function.
Hao Wang +10 more
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Frontiers in Oncology, 2021 Arsenic trioxide (ATO) has been used to treat acute promyelocytic leukemia. However, it is not effective in treating solid tumors such as colorectal cancer.
Zugui Li +11 more
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Cell fusion and plasticity [PDF]
Cytotechnology, 2003 Cell plasticity is a central issue in stem cell biology. In many recent discussions, observation of cell fusion has been seen as a confounding factor which calls into question published results concerning cell plasticity of, particularly, adult stem cells.
Naohiro Terada, Joseph J. Lucas
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BMC Genomics, 2018 Background The advances in target control of complex networks not only can offer new insights into the general control dynamics of complex systems, but also be useful for the practical application in systems biology, such as discovering new therapeutic ...
Wei-Feng Guo +5 more
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