Results 11 to 20 of about 1,346,147 (353)
Confusion on Cell Fusion [PDF]
Cell fusion, whereby two cells merge to create one, has been widely described in development, but the role of cell fusion in tissue regeneration and homeostasis remains an open debate. We propose that the regenerative capacity of the gut can be fully attributed to extensive plasticity of the intestinal epithelium.
Louis Vermeulen, Rana Ramadan
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Flagging fusion: Phosphatidylserine signaling in cell–cell fusion [PDF]
Formations of myofibers, osteoclasts, syncytiotrophoblasts, and fertilized zygotes share a common step, cell-cell fusion. Recent years have brought about considerable progress in identifying some of the proteins involved in these and other cell-fusion processes.
Jarred M. Whitlock +1 more
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Virus-Mediated Cell-Cell Fusion [PDF]
Cell-cell fusion between eukaryotic cells is a general process involved in many physiological and pathological conditions, including infections by bacteria, parasites, and viruses. As obligate intracellular pathogens, viruses use intracellular machineries and pathways for efficient replication in their host target cells. Interestingly, certain viruses,
Lucie Bracq +14 more
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The hallmarks of cell-cell fusion [PDF]
Cell-cell fusion is essential for fertilization and organ development. Dedicated proteins known as fusogens are responsible for mediating membrane fusion. However, until recently, these proteins either remained unidentified or were poorly understood at the mechanistic level. Here, we review how fusogens surmount multiple energy barriers to mediate cell-
Javier M. Hernández +1 more
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Cell fusions are important to fertilization, placentation, development of skeletal muscle and bone, calcium homeostasis and the immune defense system. Additionally, cell fusions participate in tissue repair and may be important to cancer development and progression.
Larsson, Lars-Inge +2 more
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Role of hypoxia in promoting migration and cell fusion of urine-derived stem cells
Objective To explore the effect of hypoxia on cell migration and fusion of urine-derived stem cells (USCs) in vitro, and observe the changes in cytoskeleton and cell polarity during the process.
ZHANG Nannan, HU Chaoqun, HE Yun
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“Keep on rolling”: circulating cells in a botryllid ascidian torpor
Hemocytes of the colonial tunicate Botrylloides leachii play important roles throughout the animal’s life span, including transport and storage of nutrients, respiration, regeneration, budding, sexual reproduction, defense responses, and tunic generation.
Yosef Hyams +6 more
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Regulation of cell-cell fusion by nanotopography [PDF]
AbstractCell-cell fusion is fundamental to a multitude of biological processes ranging from cell differentiation and embryogenesis to cancer metastasis and biomaterial-tissue interactions. Fusogenic cells are exposed to biochemical and biophysical factors, which could potentially alter cell behavior.
Emily R. Kinser +12 more
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Cell fusion and plasticity [PDF]
Cell plasticity is a central issue in stem cell biology. In many recent discussions, observation of cell fusion has been seen as a confounding factor which calls into question published results concerning cell plasticity of, particularly, adult stem cells.
Naohiro Terada, Joseph J. Lucas
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Background The advances in target control of complex networks not only can offer new insights into the general control dynamics of complex systems, but also be useful for the practical application in systems biology, such as discovering new therapeutic ...
Wei-Feng Guo +5 more
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