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Cell-Cell Fusion

Science, 2012
Cell Biology![Figure][1] CREDIT: TSUKASA OIKAWA Osteoclasts are cells that promote bone remodeling, and their hyperactivity is linked to bone-destructive disorders, including osteoporosis. Activated osteoclast precursors develop columnar actin structures, known as podosomes, which are similar to the invadopodia observed in invasive cancer cells ...
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Lysolecithin and Cell Fusion

Nature, 1970
Lysolecithin will induce cell fusion in several different types of cell, and both multinucleated syncytia and heterokaryons can be formed.
A R, Poole, J I, Howell, J A, Lucy
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Antibody-targeted cell fusion

Nature Biotechnology, 2004
Membrane fusion has many potential applications in biotechnology. Here we show that antibody-targeted cell fusion can be achieved by engineering a fusogenic viral membrane glycoprotein complex. Three different single-chain antibodies were displayed at the extracellular C terminus of the measles hemagglutinin (H) protein, and combinations of point ...
Takafumi, Nakamura   +7 more
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Cell fusion during development

Trends in Cell Biology, 2007
Most readers of this review originated from a sperm-egg fusion event. Cell fusion is a process that is crucial at many intersections later during development. However, we do not know which molecules (fusogens) fuse the membranes of gametes to form zygotes, myoblasts to form myotubes in muscles, macrophages to form osteoclasts in bones, or ...
Meital, Oren-Suissa   +1 more
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ADAMs and cell fusion

Current Opinion in Cell Biology, 1996
Members of the ADAM family (membrane proteins with a disintegrin and metalloprotease domain) have been implicated in several cell-interactive events, including cell-cell fusion. Recent evidence implicates three ADAMs, fertilin-alpha, fertilin-beta, and meltrin-alpha, in sperm-egg fusion and myoblast fusion.
A P, Huovila, E A, Almeida, J M, White
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Mechanisms of cell fusion

Nature, 1975
WE report new findings on the chemically-induced fusion of hen erythrocytes and discuss possible ways in which the lipid and protein/glycoprotein components of membranes may behave during the process of membrane fusion. Our observations are consistent with Poste and Allison's1 idea that the aggregation of intrinsic membrane proteins is important in ...
Q F, Ahkong   +3 more
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Cell Fusion-Induced Reprogramming

2010
Genomic reprogramming can be accomplished by five different types of methods: nuclear transfer, cell fusion, in vitro culture, introduction of egg extract, and transduction of transcription factors. We have shown that fusion-induced reprogramming is an efficient method for reprogramming differentiated somatic cells to a pluripotential state ...
Jeong Tae, Do, Hans R, Schöler
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Signal for cell fusion

Nature, 1976
THE mating of the gametes of Ulva mutabilis1 occurs essentially as described for Chlamydomonas2,3 When the gametes are mixed, they cluster and agglutinate with the tips of their flagella. Pairs consisting of a (+) and (−)-gamete leave the cluster, the cell bodies are brought together and fusion initiated.
A, Lovlie, E, Bryhni
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Cell fusion and nuclear fusion in plants

Seminars in Cell & Developmental Biology, 2016
Eukaryotic cells are surrounded by a plasma membrane and have a large nucleus containing the genomic DNA, which is enclosed by a nuclear envelope consisting of the outer and inner nuclear membranes. Although these membranes maintain the identity of cells, they sometimes fuse to each other, such as to produce a zygote during sexual reproduction or to ...
Daisuke, Maruyama   +2 more
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CELL FUSION

Naked plant cells called as protoplast. protoplant can be called as a functional individual. Cell with plasma membrane as outermost layers and the only barrier between environment and the cell contents. Cell fusion is a cellular process in which several uninucleate cells combine to form a multinucleate cell fusion called as cell - cell fusion is a ...
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