Results 221 to 230 of about 1,323,463 (353)

A Novel C19orf47‐AKT2 Chimeric RNA Generated by Cis‐Splicing of Adjacent Genes Is Associated With Glioblastoma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Malignant gliomas pose significant therapeutic challenges. This study aimed to identify and characterize a novel chimeric RNA in glioma and assess its clinical and functional significance for precision treatment. Methods The C19orf47‐AKT2 chimeric RNAs were identified through RNA sequencing and validated by polymerase chain reaction.
Zihan Wang, Bowen Ni, Kezhi Wu, Qi Zhang, Jinglin Guo, Runwei Yang, Ziyu Wang, Guozhong Yi, Guanglong Huang, Minyi He, Yimin Xu, Yawei Liu   +11 more
wiley   +1 more source

Cell fusion dynamics: mechanisms of multinucleation in osteoclasts and macrophages. [PDF]

Inflamm Regen
Sabe H, Yahara Y, Ishii M.
europepmc   +1 more source

Epithelial mechanics are maintained by inhibiting cell fusion with age in Drosophila.

J Cell Sci, 2023
Dehn AS, Duhaime L, Gogna N, Nishina PM, Kelley K, Losick VP.   +5 more
europepmc   +1 more source

A Multifunctional Delivery System for Remodulating Cell Behaviors of Circulating Malignant Cells to Prevent Cell Fusion. [PDF]

Adv Sci (Weinh), 2023
Han D, He XY, Huang Y, Gao M, Guo T, Ren XH, Liao XR, Chen XS, Pang X, Cheng SX.   +9 more
europepmc   +1 more source

Expression of human adenosine deaminase after fusion of adenosine deaminase-deficient cells with mouse fibroblasts

, 1978
Michael J. Siciliano, Mary R. Bordelon, Peter Köhler   +2 more
openalex   +1 more source

Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia, Stephane Rodriguez, Emilie Dugast, Christine Lebrun‐Frenay, Eric Thouvenot, Jérôme de Sèze, Emmanuelle Le Page, Sandra Vukusic, Inès Doghri, Eric Berger, Olivier Casez, Pierre Labauge, Aurélie Ruet, Catarina Raposo, Fabienne Le Frère, Arnaud B. Nicot, Sandrine Wiertlewski, Pierre‐Antoine Gourraud, Laure Michel, Laureline Berthelot, David‐Axel Laplaud   +20 more
wiley   +1 more source

Cell-cell fusion in cancer: The next cancer hallmark? [PDF]

Int J Biochem Cell Biol
Shultes PV, Weaver DT, Tadele DS, Barker-Clarke RJ, Scott JG.   +4 more
europepmc   +1 more source

Identification of a common secondary mutation in the Neurospora crassa knockout collection conferring a cell fusion-defective phenotype. [PDF]

Microbiol Spectr, 2023
Montenegro-Montero A, Goity A, Canessa PF, Larrondo LF.   +3 more
europepmc   +1 more source

Cell fusion and somatic cell genetics [PDF]

, 1979
Yoshio Okada
openalex   +1 more source

Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó, Igor Stevanovski, Germán Morís, Roger Collet‐Vidiella, Alba Segarra‐Casas, Lidia González‐Quereda, Benjamín Rodríguez‐Santiago, Pia Gallano, Rodrigo Alvarez, Ana Vesperinas, Rosa Blanco, Beatriz San‐Millán, Carmen Navarro, Isabel Illa, Gianina Ravenscroft, Ira W. Deveson, Eduard Gallardo, Montse Olivé   +17 more
wiley   +1 more source