Influence of the ionophore A 23 187 on myogenic cell fusion [PDF]
, 1975 C. Schudt, Dirk Pette
openalex +1 more source
Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
FEBS Open Bio, EarlyView.We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo +2 more
wiley +1 more source
Multi-stage intermediate fusion for multimodal learning to classify non-small cell lung cancer subtypes from CT and PET [PDF]
arXivAccurate classification of histological subtypes of non-small cell lung cancer (NSCLC) is essential in the era of precision medicine, yet current invasive techniques are not always feasible and may lead to clinical complications. This study presents a multi-stage intermediate fusion approach to classify NSCLC subtypes from CT and PET images. Our method
arxiv
Rescue of infectious SV40 after fusion between dfferent SV 40-transformed cells.
, 1968 Barbara B. Knowles +3 more
openalex +1 more source
FEBS Open Bio, EarlyView.FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley +1 more source
Architected Lattices with a Topological Transition
Advanced Engineering Materials, EarlyView., 2023 This article develops topological metamaterials showing multidirectional two‐step deformation under compression by embedding contact‐enabled topological mechanisms into lattice structures. Experiments on 3D‐printed 2D and 3D lattices and finite element simulations are conducted to demonstrate the working principle of the topological metamaterials.
Shivam Agarwal, Lihua Jin
wiley +1 more source
A pseudovirus-based method to dynamically mimic SARS-CoV-2-associated cell-to-cell fusion and transmission [PDF]
Acta Biochim Biophys Sin (Shanghai), 2023 Sheng X +5 more
europepmc +2 more sources
Controlling Trophoblast Cell Fusion in the Human Placenta-Transcriptional Regulation of Suppressyn, an Endogenous Inhibitor of Syncytin-1. [PDF]
Biomolecules, 2023 Sugimoto J +4 more
europepmc +1 more source
Retention of purified proteins in resealed human erythrocyte ghosts and transfer by fusion into cultured murine recipient cells [PDF]
, 1976 Wolfgang Wille, Klaus Willecke
openalex +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source